A Case of Neonatal Hemolytic Disease due to Anti-c Isoimmunization |
Hwan Sup Kang, Hyo Sup Joo, Chong Woo Bae, Suk Chul Kang, Chang Il Ahn |
Department of Pediatrics,College of Medicine,Kyung Hee University,Seoul, Korea |
抗一C 抗體에 의한 신생아 同種免疫性 용혈성 질환 1 례 |
강환섭, 주효섭, 배종우, 강석철, 안창일 |
경희대학교 의과대학 소아과학교실 |
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Abstract |
A 40 hours old female neonate was admitted to the Pediatric Ward of Kyung Hee Unive-
rsity Hospital due to severe jaundice. Laboratory work up showed typical pictures of immune
hemolytic anemia. But there was no incompatibility of ABO and Rh(D) systems between
the baby and mother.
Minor blood groups were examined by Reagent Red Cells Selectogen and Antigram. High
titer (1 : 125) of anti-c antibody was detected in mother’s serum. Emergency exchange
transfusion was performed with A, Rh(D) (+) blood, resulted in excellent recovery.
This case is the first report of c-isoimmunization in Korean neonate.
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Key Words:
Neonatal hemolytic disease, Minor group incompatibility, Anti-C isoimmunization |
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