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Review Article
Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy
Jung-Rim Yoon, Heung Dong Kim, Hoon-Chul Kang
Clin Exp Pediatr. 2013;56(8):327-331.   Published online August 27, 2013

The ketogenic diet (KD) is an established, effective, nonpharmacologic treatment for children with pharmacoresistant epilepsy. Although the KD is the most well-established dietary therapy for epilepsy, it is too restrictive and is associated with serious complications; therefore, alternative lower-fat diets, including a modified Atkins diet and low-glycemic index diet, have been developed. Recent ongoing clinical evidence suggests that other dietary...

Original Article
Serum Fatty Acid and Carnitine Levels in Obese Children with Fatty Livers
Jin Bum Lee, Jae Won Lee, Young Mi Hong
Clin Exp Pediatr. 2002;45(9):1083-1089.   Published online September 15, 2002
Purpose : The prevalence of obese children has recently increased. Obesity is known to be associated with complications such as hypertension, fatty liver, hyperlipidemia, and insulin resistance. L-carnitine is an essential cofactor for the transport of long chain fatty acids into mitochondria for β-oxidation. The purpose of this study is to measure serum free fatty acid and carnitine levels, and...
Changes of Serum Fatty Acid and Carnitine Levels after Administration of L-carnitine in Rats
Jae Won Lee, Young Mi Hong
Clin Exp Pediatr. 2002;45(9):1075-1082.   Published online September 15, 2002
Purpose : Obesity is known to be associated with hypertension, dyslipidemia, and fatty liver and is thought to be associated with increased levels of free fatty acids. One of the strategies for decreasing free fatty acid levels is stimulation of hepatic lipid oxidation with L-carnitine. Carnitine is an essential cofactor for transport of long-chain fatty acid into mitochondria for oxidation....
Sudden Unexpected Death in Infancy (Analysis of 34 Cases Including 13 Autopsies)
Yeo Ok Moon, Hee Kyoung Choi, Jeoung-A Her, Woo Jong Shin, Myoung-A Kim, Seong Yong Lee, Seong Hee Jang, Eun Sil Dong, Chong Jae Kim, Young Min Ahn, Je Geun Chi
Clin Exp Pediatr. 2002;45(9):1065-1074.   Published online September 15, 2002
Purpose : The purpose of this study is to analyze the epidemiologic characteristics of sudden unexpected death in infancy and to evaluate the importance of postmortem autopsy. Methods : We reviewed, retrospectively, medical records of 34 infants admitted to Kangnam General Hospital from January 1987 to December 2001 because of sudden unexpected death. We investigated the cause of death through medical...
Serum Lipid Levels and Fatty Acid Metabolism in the Rat with Adriamycin Induced Cardiomyopathy
Young Mi Hong, Hye Ran Yoon
Clin Exp Pediatr. 2000;43(11):1480-1487.   Published online November 15, 2000
Purpose : Adriamycin induced cardiomyopathy is irreversible and may procede to clinical congestive heart failure. Recently, it has been suggested that adriamycin may exert cardiomyopathy due to inhibition of transport across mitochondrial membranes mediated by the carnitine palmitoyltransferase system(CPT I). The effect of adriamycin on fatty acid metabolism according to cumulative dose was not clarified. The purpose of this study...
Serum Lipids and Fatty Acids According to the Type of Feeding in Children
Kyung Hwan Oh, Jae Ock Park, Chang Hwi Kim, Sang Mann Shin
Clin Exp Pediatr. 1997;40(8):1098-1103.   Published online August 15, 1997
Purpose : Lipids and fatty acids are very important for brain and nervous system in growing children. This study was carried out to compare the composition of serum lipids and fatty acids according to the type of feeding in children. Methods : One hundred and twenty two children aged from 5 month to 24 month who visited Soonchunhyang University Hospital from Mar. 1995 to...
A Study on Free Fatty Acid and Albumin Levels in Breast Milk.
Eun Young Kwak, Sang Kee Park, Chang Soo Ra
Clin Exp Pediatr. 1990;33(3):291-298.   Published online March 31, 1990
Breast milk has been the principal roles of feeding infants all over the world. Fatty acid in breast milk is a very important source of energy and a-lactalbumin is a specipic protein that is necessary for optimal growth and development of infants. The free fatty acid and albumin levels in breast milk from 128 korean mothers were analysed from January to August 1988. A...
A Case of Adrenoleukodystrophy.
Kee Sung Yang, Soo Tack Bae, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1989;32(3):430-437.   Published online March 31, 1989
We experienced a case of Adrenoleukodystrophy (ALD), which is a genetically determined metabolic disorder associated with progressive demyelination of brain white matter and adrenal insuficiency. An 11 year old male revealed rapidly evolving neuologic progression, decreased adrenal reserve, increased plasma content of very long chain fatty acids (VLCFAs) and typical radiological findings. We report here the clinical findings of this patient with brief review of...
Diagnostic Significance of Free Fatty Acid, Lipase and beta-Glucuronidase in Breast Milk Jaunce.
Kyoung Ok Lee, Soon Hak Kwon, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1988;31(5):559-565.   Published online May 31, 1988
Free fatty acids, lipase activy and β-glucuronidase activity were measured in samples of breast milk collected from mothers of infants with and without breast milk jaundice. The free fatty acids, lipase and β-glucuronidase values in the breast milk from mothers with jaundiced infants were 7.5 ±6.5 mM/L, 5.3 ±3.2 mM/min/ml and 14.6 ±9.6 nM/min/ml respectively. In the group of mothers of infants without jaundice,...
Lipid Composition of Serum HDL and Fatty Acid Composition of Serum Cholesteryl Esters in Newborn.
Jung Hee Kim, Dong Wook Kim, Dae Deok Ahn, Jung Kwon Lee, Yoon Ja Kim, Jung Chull Kim, Tai Ho Chung
Clin Exp Pediatr. 1985;28(12):1190-1195.   Published online December 31, 1985
Lipid consumption in early life has been implicated with atherosclerosis in later life. It has been also claimed that lipids contents of serum in early life would reflect coronary atherosclerosis in later life. Present study has undertaken to look for the composition of serum HDL and fatty acid composition of serum cholesteryl esters in newborns. Levels of high density lipoprotein...