The 18q-syndrome is a deletion disorder that occurs in humans. Clinical symptoms are mental retardation, craniofacial anomalies, skeletal deformity, seizure, and hearing loss. 18q- deletion occurs over a broad region, spanning the interval from 18q22.2 to 18qter rather than a single critical region containing 18q. We experienced a case of 18q-syndrome in a male child. It was diagnosed by clinical... |
Purpose : This study was performed to observe the utilization of ultrasonography in locating the position of UAC and to compare the position with anatomical landmarks seen on radiography. Methods : Optimal position is when the catheter tip is located between T6-T10 or L3-L5 by anteroposterior radiography(AP-R) and above the diaphragm by cross-table lateral radiography(CTL-R). Ultrasonographic studies used a Hewlett Packard... |
Purpose : Long-term steroid therapy for various glomerular disorders in children has been known to decrease serum Vit D3 level and develop osteomalacia. The aim of this study was to observe the effect of long-term steroid therapy on growth and bone density in children with nephrotic syndrome. Methods : Bone density of 17 steroid-treated nephrotic syndrome was compared with that of... |
Purpose : The development of fever in neutropenic cancer patients is frequently a sign of infection. Infection remains the major cause of death in the patient with cancer, primarily as a consequence of the profound alterations of normal host defences which result from the malignancy, its treatment or both. Fever in the patient with neutropenia is generally recognized as an indication of the need... |
Purpose : The purpose of this study was to standardize the somatosensory evoked potential(SEP) latency and amplitude of healthy preterm infants according to the postconceptional age. Methods : The median nerve SEPs were recorded in 30 healthy preterm infants who were followed up until 6 months and were neurodevelopmentally normal. Results : The mean peak latency and interpeak amplitude were following : P0=20.89±6.09(msec), N1=26.32±5.18, P1=31.16±6.59, N2=36.52±7.22... |
Purpose : Urinary red blood cell morphology has been used to localize the site of hematuria in the urinary tract. But the pathologic mechanism for dysmorphic urinary red blood cells remains undefIned. Our study was undertaken to investigate the mechanism of dysmorphic urinary RBCs in glomerular hematuria. We have attempted to reproduce in vitro the changes that occur in red cell... |
Bone mineral densitometry is a useful procedure for the early detection of metabolic bone diseases and bone density changes caused by long term drug use. Dual energy X-ray absorpt- iometry(DEXA), a recently developed diagnostic radiologic method for evaluating bone mineral density is widely used because of its high sensitivity, easily obtaine results. and low dose radi- ation exposure. The study... |
Purpose : Recent development in ultrasonic Doppler instrumentation have allowed the direct noninvasive assessment of human renal artery blood flow. The authors conducted this study to assess noninvasive characterization of normal renal artery blood flow variables hopping to establish standards in normal children. Methods : A total 97 normal Subjects(below the age 3 years) were examinated using by 2-D and... |
Xanthogranulomatous pyelonephritis in childhood is a rare chronic pyelonephritis often assodiated with calculi of urinary tract obstruction, with a clinical presentation of renal mass. A 3-year old boy was admitted to Korea University Hospital complaining of intermittent fever and palpable mass at right upper quadrant of the abdomen. The CBC revealed increased ESR and the finding of iron deficientcy anemia.... |
The hyperlipoproteinemias are the disturbance of lipid transport resulted from accelerated synthesis or retarded degradation of lipoproteins that transport cholesterol and trigycerides through plasma. These diseases are classified as type I, type IIa, type IIb, type III, type IV, type V, and hyper-α-triglyceride levels due to increases in both VLDL and chylomicrons and lipoprotein electrophoresis shows increases pre-β, β, and... |
Schölein-Henoch purpura is a generalized small vessel vasculitis characterized by non-thrombocytopenic purpura, arthritis, abdominal pain and nephritis. In 1913 Osler described an allergic purpura associated with hemiplegia. After then Lewis et al. Reported the cases of Schölein-Henoch purpura associated with convulsion, coma, confusion, intracranial hemorrhage, and chorea, CNS complication has been reported in 1-8% of children and subsided spontaneously in... |
Miescher syndrome comprises congenital acanthosis nigricans, hypertrichosis, failure to thrive and short stature, dysmorphism especially of the jaws and oral cavity. Insulin-resistant diabetes mellitus, and a characteristic general appearance. This report concerns a rare case of 12-year-old girl having insulin resistant diabetic mellitus with Miescher syndrome. The relevant literature was reviewed. |
The frequent occurrence of hematuria in children necessitates diagnostic evaluation. Hematuria may occur with either renal or lower urinary tract disease. Clarification of the etiology of hematuria, whether microscopic or gross, is facilited by localizing the site of bleeding to the kidney(glomerular) or the lower urinary tract (non-glomerular). The mean cellular volume (MCV) of urinary red blood cells (RBCs) of... |
The long term administration of anti-convulsants on children with convulsive disorders may cause osteomalacia, depending on the dosage, duration, type and combination of anti-convulsants administred. Fifteen children, comprising 10 male and 5 female, dignosed with convulsive disorders and administered with phenobarbital for a long term period of more than 9 months but less than 84 months and 15 healthy children... |
To determine the types of metabolic acidosis using anion gap in acute infantile diarrhea and to correlate it with clinical outcome, we examined 103 infants admitted with acute diarrhea. The serum electrolytes (sodium, potassium, chloride, phosphorus), creatinine, CO2 content and anion gap were measured on first admission day. They were classified group A with normal anion gap (8~16 mEq/L) and... |
A clinical and statistical study was performed on 213 neonates of hyperbilirubinemia who were admitted to department of pediatrics of Korea University Hospital from Jan. 1989 to Jun. 1991. And we studied the difference between ABO compatible group and incompatible group, such as, day of appe5rance of hyperbilirubinemia, tendency of bilirubin concentration change, reticulocyte, hemoglobin and duration of hyperbilirubinemia. The following... |
Dyke-Davidoff Masson syndrome is a rare disorder which developed hemiatrophy of brain, enlargement of ventricles and prominet pneumatrization of pertous pyramid of the temporal bone. It manifests hemiparesis, varying type seizure, and mental retardation. We experienced two cases of Dyke-Davidoff-Masson Syndrome, in a 6/12 year-old boy and a 1,10/12 year-old girl who were admitted to our department of pediatrics, because of... |
Methylmalonic acidemia is an inborn error of metabolism, which is characterized by excretion of large amount of methylmalonate, and is transmitted as an autosomal recessive traits. The clinical symptoms begin in early life and are recurrent vomiting, lethargy, dehydration, failure to thrive. Laboratory findings show ketosis, metabolic acidosis, methymalonic aciduria with normal serum cobalamin level, hyperammonemia, pancytopenia. Two treatment regi- mens exist and should... |
Neonatal spontaneous pneumomediastinum is a rare phenomenon which is observed in case of respiratory distressed, meconium stained and meconium aspirated neonate. In certain state, air can leak from the ruptured alveoli into the pulmonary interstitium and movement of this air along the vascular structures may result in pneumomediastinum. We experienced a case of spontaneous pneumomediastinum, in a 3 day-old male infant (43+5 wks gestational... |