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Purpose : High dose intravenous immunoglobulin(IVIG) therapy is effective in reducing the
incidence of coronary artery aneurysm in Kawasaki disease(KD) patients, however, the precise
mechanisms by which IVIG reverses the immune activation is unknown.
Methods : The sera and peripheral mononuclear cells(PBMCs) were obtained from 10 KD patients
in the acute stage(24 hrs before) and 24 hrs after one dose of IVIG(2g/kg) treatment. We
measured... |
