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Original Article

iption Factor NF-κB Caused by Acute Hypoxia in the Heart

Chan Uhng Joo, Woo Suk Juhng, Jae Cheol Kim, Ho Keun Yi

Clin Exp Pediatr. 2002;45(9):1106-1113. Published online September 15, 2002

Purpose : Nuclear factor-κB(NF-κB) is now recognized as playing a potential role in programmed cell death and the adaptive response to various stress. Cellular hypoxia is a primary manifestation of many cardiovascular diseases. It seems that vascular endothelial growth factor (VEGF) and insulin like growth factor-I(IGF-I) have a function as a protective molecule in the heart against several stress including...

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