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von Willebrand disease is a bleeding disorder characterized by a complex hemostatic defect. These
abnormalities arise from quantitative and/or qualitative abnormalities of von Willebrand factor
which circulates in plasma complexed with the factor VID procoagulant protein.
We have experienced three cases of type I von Willebrand disease in two children and their
mother. They had prolonged bleeding time and partial thromboplastin time, mildly decreased... |