Journal of the Korean Pediatric Society 1995;38(8):1141-1145.
Published online August 15, 1995.
Subacute Necrotizing Lymphadenitis (Kikuchi's Disease) in a Child with Atopic Asthma
Dong Jun Kim1, Seong Yeoub Moon1, Ha Baik Lee1, Yeong Hae Koh2
1Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea
2Department of Histopathology, Hanyang University College of Medicine, Seoul, Korea
소아 아급성 괴사성 림프절염(Kikuchi 병) 1례
김동준1, 문성엽1, 이하백1, 고영혜2
1한양대학교 의과대학 소아과학교실
2한양대학교 의과대학 조직병리학교실
Subacute necrotizing lymphadenitis (Kikuchi's disease) is an increasingly recognized cause of cervical lymphadenitis since it has been described by Japanese doctors in 1972. It generally follows a benign course, when symptoms and signs of the disease are resolved usually within 1 to 6 months. We experienced a case of subacute necrotizing lymphadenitis in a 12 year-old boy with atopic bronchial asthma highly allergic to hours dust mite. He was admitted with chief complaints of high over 39℃ and enlargement of both posterior cervical lymph nodes and left submandibular lymph nodes. His symptoms and signs were poorly unresponed to antipyretic and antibiotic therapy. Lymph node biopsy for the diagnosis revealed characteristic features of subacute necrotizing lymphadenitis. These included a well circumscribed, localized necrotizing area of the cortical and paracortical regions associated with karyorrhexis and presence of large lymphocytes and histiocytes. However, granulocytes and eosinophils were absent. After prednisolone administration, the smptoms and signs were dramatically improved, and now he keeps doing well.
Key Words: Subacute necrotizing lymphadenitis, Cervical lymph node, Asthma

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