Clinical and Radiological Analysis of Reversible Posterior Leukoencephalopathy Syndrome in Children |
Hae-Ri Lim, Hye-Eun Seo, Sun-Hak Kwon |
Department of Pediatrics, college of Medicine, Kyungpook National University, Daegu, Korea |
소아에서 가역성 후두부 백질 뇌증 증후군의 임상적, 방사선학적 특성에 대한 고찰 |
임해리, 서혜은, 권순학 |
경북대학교 의과대학 소아과학교실 |
Correspondence:
Sun-Hak Kwon, Email: shkwon@knu.ac.kr |
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Abstract |
Purpose : Reversible posterior leukoencephalopathy syndrome is a complex disorder with characteristic clinical and radiologic findings that mainly involve the white/gray matter of the parieto-occipital lobes. The purpose of this study was to determine its clinical and radiological characteristics.
Methods : A total of 15 pateints were involved in the study. Their medical records and radiological features of brain MRI were retrospectively reviewed and analyzed.
Results : Fifteen pateints were involved. (9 males and 5 females). The patients' ages ranged from 2-20 years (mean age : 10 years). The brain MRI revealed fairly symmetric areas of increased T2 signal involving both white and gray matter of parieto-occipital regions. The condition seemed to be associated with cyclosporin A and steroid therapy or a variety of other conditions in which blood pressure rises acutely.
Conclusion : Reversible posterior leukoencephalopathy syndrome is a complicated neurological condition, but a better understanding of this complex syndrome may obviate unnecessary investigations and lead to prompt and appropriate management of the associated problems. |
Key Words:
Leukoencephalopathy, Seizure, Cyclosporin, Steroid |
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