Journal of the Korean Pediatric Society 1991;34(2):180-189.
Published online February 28, 1991.
A clinical study on influences of premature rupture of membranes in the newborn infant.
Ji Sun Cho, Young Sun Ko, Soon Ok Byun, Ji Sub Oh
Department of Pediatrics, Wallace Memorial Baptist Hospital, Pusan, Korea
조기양막파수가 신생아에 미치는 영향에 대한 임상적 고찰
조지선, 고영선, 변순옥, 오지섭
왈레스기념 침례병원 소아과
Received: 13 August 1990   • Accepted: 26 September 1990
Abstract
A clinical study was made on 607 newborns of mothers with premature rupture of membrane (PROM group) and 5,775 newborns of mothers without ruptured membrane Baptist Hospital from January 1987 to December 1989. The results are summarized as follows: 1) The overall incidence of PROM was 9.5% with little yearly variations. 2) 11.9% of all babies with PROM were bom prematurely, significantly higher than the incidence of control group (4.1%). 3) The incidence of birth weight below 2500gm in PROM group (12.4%) was significantly higher than in the control group (6%). 4) Twenty-eight percent of term deliveries and fifty-seven percent of preterm deliveries occurred beyond 24 hours after PROM. A positive correlation was found between prematurity and time interval after PROM. 5) Morbidity and mortality incidences in the PROM group were 33% due to sepsis, 5.9% due to asphyxia, 0.8% due to RDS and 3.1% due to neonatal death. 6) The incidence of sepsis in the PROM group (3.3%) was significantly higher than in the control group (0.9%). The incidence was increased proportionally with prematurity and with increasing time after PROM. With respect to etiologic bacteria, S.epidermidis was the most frequently observed in both groups. 7) The incidence of neonatal asphyxia in the PROM group (5.9%) was significantly higher than in the control group (1.6%) and the premature babies had greater incidence in both groups. The incidence after 24 hours was greater than the incidence before 24 hours. 8) Neonatal respiratory distress syndrome (RDS) was found in 0.8% of babies with 0.8% of babies with PROM. Premature babies had a higher incidence of RDS in control and PROM groups, but latter had an incidence amounting to 1/2 of the former. In addition it tended to diminish with increasing time after PROM. 9) Neonatal death was higher in PROM (3.1%) than in the control group (0.8%) and the premature babies had a greater incidence in both groups. This also increased with time after PROM.
Key Words: Premature rupture of membranes, Prematurity, sepsis, Neonatal asphyxia, RDS, Neonatal death


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