| Preventive Effect of Single Dose Vitamin K for the Late Hemorrhagic Disease of Infancy. |
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Young Youn Choi, Hwa Il Kwag, Byung Hee Kim, Tai Ju Hwang |
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Department of Pediatrics, Chonnam University Medical School, Kwangju, Korea |
| 비타만 K 1회 투여에 의한 영아기
출혈성 질환의 예방 효과 |
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최영륜, 곽화일, 김병희, 황태주 |
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전남대학교 의과대학 소아과학교실 |
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Received: 27 September 1989 • Accepted: 3 November 1989 |
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| Abstract |
To evaluate the preventive effect of single dose vitamin K for the late hemorrhagic disease of
infancy, hepaplastin test was carried out in 15 breast-fed and 12 formula-fed babies. Vitamin Ki lmg
was injected immediately after the birth intramuscularly and the test was performed the 1st (before
vitamin k administration), 3rd, 7th, 28th days of life and the end of the 2nd and 4th months of life
(after administration).
Results
obtained were summarized as follows:
The level (%) of hepaplastin was significantly elevated in both breast-fed and formula-fed groups
until the 4th month after administration of vitamin K comparing with the level before administration.
The difference of hepaplastin level between breast-fed and formula-fed group was not observed
until the 28th day of life. But it was significantly higher in formula-fed than in breast-fed group at the
2nd and 4th months of life
The cases below the 35% of hepaplastin level after administration of vitamin K were significantly
decreased until the 2nd month in breast-fed group and until the 4th month except the 3rd day in
formula-fed group. But difference was not observed between groups |
| Key Words:
Vitamin K, Late hemorrhagic disease of infancy, Hepaplastin test, Breast-fed, Formula-fed |
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