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Original Article
Other
Korean parents’ perceptions of the challenges and needs on school re-entry during or after childhood and adolescent cancer: a multi-institutional survey by Korean Society of Pediatric Hematology and Oncology
Jun Ah Lee, Jae Min Lee, Hyeon Jin Park, Meerim Park, Byung Kiu Park, Hee Young Ju, Ji Yoon Kim, Sang Kyu Park, Young Ho Lee, Ye Jee Shim, Heung Sik Kim, Kyung Duk Park, Yeon-Jung Lim, Hee Won Chueh, Ji Kyoung Park, Soon Ki Kim, Hyoung Soo Choi, Hyo Seop Ahn, Jeong Ok Hah, Hyoung Jin Kang, Hee Young Shin, Mee Jeong Lee
Clin Exp Pediatr. 2020;63(4):141-145.   Published online November 14, 2019
Question: What are the parental needs and challenges when their children return to school after cancer?
Finding: In addition to scholastic aptitude-oriented programs, emotional and psychosocial support is necessary for a successful return to school.
Meaning: Pediatric oncologists should actively engage in improving oncology practices to better integrate individualized school plans and educate peers and teachers to improve health literacy to make them understand the needs of children with cancer.
Review Article
Bone mineral density deficits in childhood cancer survivors: Pathophysiology, prevalence, screening, and management
Min Jae Kang, Jung Sub Lim
Clin Exp Pediatr. 2013;56(2):60-67.   Published online February 25, 2013

As chemotherapy and other sophisticated treatment strategies evolve and the number of survivors of long-term childhood cancer grows, the long-term complications of treatment and the cancer itself are becoming ever more important. One of the most important but often neglected complications is osteoporosis and increased risk of fracture during and after cancer treatment. Acquisition of optimal peak bone mass and...

Original Article
The metabolic syndrome and body composition in childhood cancer survivors
Young Bae Sohn, Su Jin Kim, Sung Won Park, Se-Hwa Kim, Sung-Yoon Cho, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Jae Hoon Chung, Hong Hoe Koo, Dong-Kyu Jin
Clin Exp Pediatr. 2011;54(6):253-259.   Published online June 30, 2011
Purpose

Long-term survivors of childhood cancer appear to have an increased risk for the metabolic syndrome, subsequent type 2 diabetes and cardiovascular disease in adulthood compared to healthy children. The purpose of this study was to investigate the frequency of the metabolic syndrome and associated factors in childhood cancer survivors at a single center in Korea.

Methods

We performed a retrospective review of...

Review Article
Late physical effects of childhood cancer survivors
Young-Ho Lee
Clin Exp Pediatr. 2010;53(4):477-480.   Published online April 15, 2010
Advances in research and medical and supportive care have contributed to a growing population of adults formerly treated for childhood cancer. History of cancer and its therapy can have significant life-long health implications. Late effects of cancer therapy can be insidious on onset, occur outside the pediatric age, and contribute to premature morbidity and mortality. In this review, I have focused on the...
Psychosocial aspects of childhood cancer survivors
Jong Jin Seo
Clin Exp Pediatr. 2010;53(4):471-476.   Published online April 15, 2010
The majority of childhood cancer survivors and their families will be psychologically healthy, but may desire and benefit from preventive care. A significant portion of the survivor population will be psychosocially distressed in various aspects by their harsh experience of long cancer treatment, and may warrant professional intervention and treatment. Pediatricians should be aware of the late psychological effects that can occur a...
Long-term follow-up study and long-term care of childhood cancer survivors
Hyeon Jin Park
Clin Exp Pediatr. 2010;53(4):465-470.   Published online April 15, 2010
The number of long-term survivors is increasing in the western countries due to remarkable improvements in the treatment of childhood cancer. The long-term complications of childhood cancer survivors in these countries were brought to light by the childhood cancer survivor studies. In Korea, the 5-year survival rate of childhood cancer patients is approaching 70%; therefore, it is extremely important to undertake...
Original Article
Capsaicin induced apoptosis and the enhanced anticancer effect of anticancer drugs in cancer cells
Sun Young Kim, You Jin Lee, Eun Hye Park, Ho Keun Yi, Dae Sun Jo, Jung Soo Kim, Pyoung Han Hwang
Clin Exp Pediatr. 2008;51(3):307-314.   Published online March 15, 2008
Purpose : Capsaicin, the major pungent ingredient in red pepper, has long been used in spices and food additives. It has been recently shown to induce apoptosis in several cell lines through a not well known mechanism. The aim of this study was to investigate the apoptosis-inducing effect of capsaicin on gastric cancer cells, and to provide valuable information concerning...
Serum ghrelin and leptin concentrations in children with cancer : comparisons with normal children
So Hyun Park, Min Ho Jung, Nac Gyun Chung, Byung-Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2007;50(9):905-911.   Published online September 15, 2007
Purpose : Ghrelin, being secreted from the stomach, stimulates growth hormone secretion and controls energy homeostasis by increasing appetite. Leptin, being secreted from the adipocytes, controls weight and energy homeostasis by decreasing appetite. Leptin concentration is reported to increase after childhood cancer therapy. This study was aimed to compare ghrelin and leptin concentrations in normal children and children who received...
Etiological agents isolated from blood in children with hemato-oncologic diseases (2002-2005)
So-Hee Kim, Young-Ah Lee, Byung-Wook Eun, Nam-Hee Kim, Jin-A Lee, Hyoung Jin Kang, Eun-Hwa Choi, Hee Young Shin, Hoan-Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 2007;50(1):56-64.   Published online January 15, 2007
Purpose : This study was performed to identify the etiologic agents and antimicrobial susceptibility patterns of organisms responsible for bloodstream infections in pediatric cancer patients for guidance in empiric antimicrobial therapy. Methods : One hundred and ninety-seven episodes of bloodstream infections that developed in 128 pediatric cancer patients were analyzed, which were identified at the Seoul National University Children's Hospital during...
Bacteremia in pediatric cancer patients : A single center study
Sun Mi Park, Byung Kyu Choe, Chun Soo Kim, Joon Sik Kim, Heung Sik Kim, Nam-Hee Ryoo
Clin Exp Pediatr. 2006;49(8):882-888.   Published online August 15, 2006
Purpose : Bacteremia is one of the major concerns in the treatment of pediatric cancer patients. This study was to determine the etiologic agents and the pattern of antibiotic susceptibilities in a single tertiary medical center. Methods : We retrospectively reviewed the medical records of the cases of bacteremia in pediatric cancer patients from 1998 to 2005 in Keimyung University Dongsan...
Follow-up Study of Children with Anthracycline Cardiotoxicity
Hyok Joo Kwon, Young Hwan Song, Soo Jung Kang, Hyoung Jin Kang, Hyoung Soo Choi, Eun Jung Bae, Hee Young Shin, Chung Il Noh, Yong Soo Yun, Hyo Seop Ahn
Clin Exp Pediatr. 2003;46(3):242-249.   Published online March 15, 2003
Purpose : We studied the relationship between anthracycline cumulative dose and anthracycline cardiotoxicity in childhood cancer and followed up 40 children with anthracycline cardiotoxicity. Methods : A retrospective study was performed in 154 children who received anthracycline chemotherapy between January 1995 to December 2000. Cardiotoxicity was defined when the left ventricular fractional shortening(FS) was below 26%; it was divided into two...
A Clinical Study on Varicella zoster Virus Infection, Relating Factors and Treatment in Pediatric Cancer Patients
Yoon Sook Chung, Su Hyun Kim, Ki Joong Kim, Hahng Lee
Clin Exp Pediatr. 2001;44(11):1289-1294.   Published online November 15, 2001
Purpose : We performed this study to contribute to the prevention and treatment of Varicella zoster virus infection in pediatric cancer patients through understanding of VZV infection, acyclovir efficacy and varicella vaccination. Methods : A retrospective study was performed by reviewing chart from January 1988 to January 2001. Results : The diseases among 19 cases were leukemia. 12 cases were solid...
The Characteristics of Febrile Neutropenia Induced by Chemotherapy
Hyung Joo Sohn, Kee Hwan Yoo, Guang Chul Lee, Sun Gyum Kim
Clin Exp Pediatr. 1997;40(10):1443-1452.   Published online October 15, 1997
Purpose : The development of fever in neutropenic cancer patients is frequently a sign of infection. Infection remains the major cause of death in the patient with cancer, primarily as a consequence of the profound alterations of normal host defences which result from the malignancy, its treatment or both. Fever in the patient with neutropenia is generally recognized as an indication of the need...
Plasma Lipid Alteration in Leukemia and Solid Tumor
Eun Sik Kang, Myoung Soon Song, Hea Jin Cheoh, Kyu Chul Choeh
Clin Exp Pediatr. 1995;38(4):529-536.   Published online April 15, 1995
Purpose : A sensitive, specific blood test to detect cancer would be of great value but the search for such a test has been fruitless so far. In actual practice, there is often a considerable interval between the point at which a tumor could have been detected and the point at which it produces symptoms as a result of tumor...
A Prospective Study of Totally Implanted Venous Access System in 19 Children with Cancer
Kyung Duk Park, Eun Sil Dong, Seong Hoon Ha, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Seong Eun Jun, Gui Won Park
Clin Exp Pediatr. 1993;36(5):687-692.   Published online May 15, 1993
A totally implanted venous access system was inserted in 19 children with cancer. The devices were utilized for the administration of antineoplastic drug, parenteral fluids, antibiotics, and blood products. Total duration of implantation was 4,046 days for 23 implanted system (range 7-445 days). Complications included cather infection (0.247/100 catheter day), occlusion (0.692/100 catheter days), and dislodgement of needle (0.643/100 catheter...
Change of NK Cell and LAK Cell Activity of Cancer Patients in Postchemotherapy Period.
Chong Sung Chung, Kyuchul Choeh, Yong Mook Choi
Clin Exp Pediatr. 1989;32(7):933-942.   Published online July 31, 1989
This study was undertaken to evaluate the Natueral-Killer (NK) cell and Lymphokine-Activated-Killer (LAK) cell activity of cancer patients for the prupose of understanding of spontaneous cell-mediated cytotoxicity (SCMC) in cancer patients and understanding of interrelationship between NK cell and LAK cell. Total 9 cases of malignant tumor (7 cases: Acute leukemia, 2 cases: malignant lymphoma) below 15 years of age, who were on remission...
Case Report
A Case of Primary Lung Cancer(Squamous cell ca.) in Children.
Soo Ryun Choi, Choong Hyun Kim, Soon Ok Byun, Ji Sub Oh, Sung Kyun Im, Ok Ji Park
Clin Exp Pediatr. 1985;28(12):1256-1260.   Published online December 31, 1985
We have experienced a case of primary lung cancer (squamous cell ca.) in a 15 years-old boy who presented with productive coughing and mild fever. The diagnosis was made through thoracic roentgenogram, thoracotomy, and biopsy. A brief review of the related literature is given.
A Case of Primary Lung Cancer(Squamous cell ca) in Children.
Yong Ae Kim, So Kyung Park, Dong Hak Shin, Sang Suk Lee
Clin Exp Pediatr. 1984;27(2):178-183.   Published online February 28, 1984
This paper presented a case of primary lung cancer (squamous cell ca) in children, found a 12 years old boy. This patient was presented chief complaints of respiratory difficulty, procuctive cough and high fever. Diagnosis of lung cancer was made thuough bronchoschopic biopsy of bronchus with sputum cytology. We thought this is unusual case and we reviewed literatures and could not find the...