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Original Article

Implication of vacA s1 Genotype of Helicobacter pylori in Children

Yae Jean Kim, Hae Young Park, Mi Ae Lee, Jeong Wan Seo

Clin Exp Pediatr. 1999;42(11):1516-1523. Published online November 15, 1999

Purpose : Recently vacA s1 genotype of Helicobacter pylori was known to be associated with enhanced inflammation and peptic ulceration. To evaluate the association of the vacA s1 genotype with enhanced inflammation and peptic ulceration in children, we performed a polymerase chain reaction(PCR) for vacA s1 genotype. Methods : Twenty-seven CLO test-positive children were enrolled. They also revealed histological detection...

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