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Original Article
Effect of hyperglycemia on mortality rates in critically ill children
Seongkuk Kim, Bo Eun Kim, Eun Ju Ha, Mi Young Moon, Seong Jong Park
Clin Exp Pediatr. 2010;53(3):323-328.   Published online March 15, 2010
Purpose : To verify the effect of hyperglycemia on mortality rates in critically ill children and to identify the blood glucose level that influences prognosis. Methods : From July 2006 to June 2008, a total of 206 patients who were admitted to the pediatric intensive care unit (PICU) at Asan Medical Center and who survived for more than 7 days...
Early stress hyperglycemia as independent predictor of increased mortality in preterm infants
Young Sun Wee, Gae Hyun Ahn, Eun Gyong Yoo, In Sook Lim, Kyu Hyung Lee
Clin Exp Pediatr. 2008;51(5):474-480.   Published online May 15, 2008
Purpose : Stress hyperglycemia is common in critically ill adult patients. It is known as a predictor of increased mortality, and intensive insulin therapy has been shown to improve the prognosis in such patients. We have investigated the relationship between early stress hyperglycemia and clinical outcomes in preterm infants. Methods : In this study, 141 preterm infants with a gestational age...
Effect of Glucocorticoid-Induced Hyperglycemia on Preventing Hypoxic-Ischemic Brain Damage by Dexamethasone in Neonatal Rat
Kook In Park, Tae Seung Kim, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1994;37(8):1035-1047.   Published online August 15, 1994
Purpose : We evaluated the protective effect of dexamethasone (DX) administration on brain damage produced in a perinatal model of cerebral hypoxia-ischemia in the rat. Since hyperglycemia has been shown to reduce hypoxic-ischemic brain injury (HI) in immature rat, we investigated the role of glucocorticoid-induced hyperglycemia in the neuroprotective mechanism of DX. Methods : Hypoxic-ischemic brain injury in 7-day-old rats was...
Risk Factors for Hyperglycemia in Children with Leukemia Receiving L-asparaginase
Min Joong Kwon, Ho Sung Kim, Kir Young Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(6):740-745.   Published online June 15, 1994
Hyperglycemia is a well-recognized side effect of L-asparaginase in remission induction therapy of acute lymphocytic leukemia. Since hyperglycemia has preceded fatal diabetic ketoacidosis or hyperosmotic nonketotic coma in some patients, early detection and treatment of this complication are important. We determined retrospectively the risk of hyperglycemia in 117 patients with leukemia who had received L-asparaginase (& prednisolone). The results were as...
Continuous Intravenous Glucose Infusion and Serum Glucose in Neonates.
Hae June Park, Jung sik Rhim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1987;30(5):499-503.   Published online May 31, 1987
Serum glucose changes by constant infusion of glucose at the rate of 8 mg/kg/min were studied in 20 neonates. Serum glucose level elevated from 41 ±8 mg/dl to 80 ±31 mg/dl within 10 minutes of infusion. In some cases hyperglycemia above 150 mg/dl was observed from 40 minutes of infusion. Constant glucose infusion was found to be useful for elevation of glucose level...
Hyperglycemia in Small Premature Neonates.
Soon Hwa Kim
Clin Exp Pediatr. 1983;26(12):1168-1172.   Published online December 31, 1983
The blood glucose response to a constant glucose infusion were measured in 36 low birth weight infants with birth weight 950 to 2,000 gm. The study includes 27 control premature infants and 9 stressed premature infants who had respiratory distress. Glucose values were similar in both the control and stressed groups in the cord and preinfusion samples. In the first postinfusion sample, hyperglycemia was...
Hyperglycemia in Stressed Premature Infants.
Heung Kyu Kim, Kyung Ho Kim
Clin Exp Pediatr. 1983;26(2):124-129.   Published online February 28, 1983
The blood glucose response to a constant glucose infusion were measured in 62 premature infants weighing 1,000 to 2,200 gm. The study includes 32 stressed premature infants who had respiratory distress, Necrotizing enterocolitis, premature rupture of membranes, sepsis and 30 control premature infants. During the first three hours of life, the glucose values were similar in both stressed and the control groups. During the four...