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Ifosfamide (IFO), one of a number of alkylating agents, has been given with Adriamycin (ADR) or Etopsoide (VP-16) to the thirteen malignant solid tumor patients (five neuroblastoma, six osteosarcoma, one rhabdomyosarcoma, one leigomyosarcoma). IFO 1.8g/m2/d was given for an hour with mensa uroprotection for the consecutive five days. All but two relapsed patients had response. The number of courses were... |