Purpose : We studied the usefulness of transcutaneous bilirubinometers in follow-up of bilirubin levels during phototherapy in neonatal jaundice patients. Methods : Transcutaneous bilirubin (TcB) was measured twice per day on 90 neonatal jaundice patients without risk factors of jaundice by transcutaneous bilirubinometer JM-103(Minolta/Hill-Rom Air-shields, Japan). TcB was measured simultaneously on the patched-forehead (TcB-PF), patched- chest(TcB-PC), unpatched-forehead (TcB-UF) and unpatched-chest (TcB-UC)... |
Purpose : We hypothesized that phototherapy, if the total serum bilirubin(TSB) is ≥14mg/dl, would decrease not only in frequency and duration, but complications due to phototherapy, such as weight loss, rash, temperature instability, feeding intolerance, and diarrhea, would decrease when compared to phototherapy TSB ≥10mg/dl after 48 hours of life in healthy term newborns without hemolysis. Methods : Forty healthy newborns... |
Purpose : Cholestylamine has been shown to release chloride ion and absorbs bile acid in the intestine, forming a nonabsorbable complex preventing enterohepatic circulation. The purpose of this study is to clarify the value of cholestylamine and the adequate dosage, in combination with phototherapy, as well as to confirm whether it shorten the duration of hospitalization. Methods : Total 80 full-term neonates with a... |
Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or... |
Purpose : Neonatal jaundice is one of the most common problems in our country leading to hospitalization. Agar is low cost, low risk, and easily fed orally; it can bind bilirubin in the intestine, decreasing its enterohepatic circulation, thereby decreasing serum bilirubin levels. At present, however, the effectiveness of agar in the prevention and treament of neonatal jaundice is quite conflicting and controversy. Recently we... |
Purpose : We performed this study in order to compare the feasibility and efficacy of the fiberoptic phototherapy with conventional phototherapy and double phototherapy with single phototherapy for the treatment of neonatal hyperbilirubinemia while watching for any possible side effects of the system. Methods : During the period of February 1994 till June 1995, randomized controlled study was performed. 130 healthy term infants with non-hemolytic... |
Purpose : Riboflavin is the most important water soluble vitamin in infant nutrition. Riboflavin is converts to flavin mononucleotide (FMN), Flavin adenine dinucleotide(FAD) and then, participiates in the metabolism of energy, protein cellular oxidation-reduction reactions as a cofactor of reactions. Also riboflavin, a light sensitive vitamin, has a maximum absorption spectrum at a wave length similar to that at which... |
Since the effect of phototherapy in the treatment of neonatal hyperbilirubinemia has been reported 30 years ago, phototherapy has been used widely for neonatal hyperbilirubinemia, but the exact mechanism and the effect of light on the human body have not been fully determined. Free bilirubin level in the serum is an important indicator for kemicterus, a complication of neonatal hyperbilirubinemia. Free bilirubin level was... |
The effects of phototherapy used in treatment of neonatal hyperbilirubinemia on peripheral blood findings were studied in full term newborns. There was no significant difference between daily mean hematocrits and WBC counts of phototherapy group and control group. The mean platelet count was not decreased during phototherapy in treated group, but significantly increased after phototherapy was stopped. 、 |
Since the report of Dr. Cremer in the 1950s the effectiveness of phototherapy in the treatment of neonatal hyperbilirubinemia has been demonstrated in many clinical trials and now become widely accepted as a routine therapeutic measure in most pediatric clinics. Considering the relatively high incidence of prematurity and neonatal jaundice especially in Asian countries, it is of great concern to... |
Warshaw reported radiat flux is closely related to distance between light source and patient for phototherapy. We tried to compare 30 cm distance (group A) frome light source to patient with 80 cm (group B) for effect of phototherapy. 1) Radiant flux were 4.68±0.3㎼/cm2/nm in group A phototherapy unit ard 1.49±0. 02㎼/cm2/nm in group B... |
The effect of phototherapy was studied between blue and white lights, and continuous and intermittent regimens in the treatment of jaundice for the low birth weights at Busan Children’s Hospital from October, 1981 to March, 1982. The results were as following: 1) The duration of phototherapy necessary to reduce serum bilirubin level below 8 mg/dl were 58.9 hours with blue light, and 102.3 hours with white... |
The effect of phototherapy on platelet counts performed on thirty premature infants weighing less than 2,300 grams and thirty fullterm infants with hyperbilirubmemia. Platelet counts were also performed on twenty nine healthy premature infants weighing less than 2,300 grams and thirty full-term infants as oontrol group. The following results were observed: 1) There was no significant difference in platelet counts during phototherapy on premature... |
Daylight phototherapy group (27 newborn infant) were compared with blue light photother- apy group (43 newborn infant) in serum total bilirubin decrements with phototherapy.; study A. For the purpose of dose-response relationship, 4 group (total 60 newborn infant) were compared the effectiveness of phototherapy based on radiant reflux (study B); Group 1, 5.46±0.65 ㎼/cm2.nm(mean±SD) Group 2,4.48±0.70 ㎼/cm2. nm (mean±SD)... |
W« studied the guidelines on the serum bilirubin concentration of 15 mg% for the management of neonatal jaundice and compared the group of serum bilirubin concentration below 15 mg% ■and the group of serum bilirubin concentration above 15 mg%. 83 cased of icteric infants without any risk factors for kernicterus, ahove 12 m.g% in serum bilirubin concentration, were born at the St. Benedict hospital... |
Riboflavin in unstable in light and has a maximum absorption at 450nm. A study was designed to determine whether riboflavin deficiency developed in neonate who received phototherapy with eight day light bulbs for hyperbilirubinemia and to get normal value of activity coefficient of erythrocyte glutathione reductase in neonate. Twenty-seven infants who received phototherapy were investigated. Thirth-eight normal infants without phototherapy... |