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Editorial
Critical Care Medicine
Is it possible to provide palliative care to pediatric patients with neurological diseases?
Young-Hoon Kim
Clin Exp Pediatr. 2024;67(8):403-404.   Published online February 15, 2024
· Patients with neurological diseases often require external mechanical support to maintain mechanical ventilation or supply.
· Little has been done to help the families of affected children make difficult decisions that carry significant physical and psychological consequences.
· The establishment of a department that provides pediatric palliative care for neurological patients should be considered.
Review Article
Developmental and Behavioral Medicine
Clinical practice guidelines for attention-deficit/hyperactivity disorder: recent updates
Tae Hoon Eom, Young-Hoon Kim
Clin Exp Pediatr. 2024;67(1):26-34.   Published online June 14, 2023
· Primary pediatricians should play a key role in the diagnosis and treatment of attention-deficit/hyperactivity disorder (ADHD).
· The Diagnostic and Statistical Manual of Mental Disorders, fifth edition, has lowered the diagnostic threshold for older teens and adults and a comorbid diagnosis with autism is now allowed.
· The American Academy of Pediatrics had added recommendation-related comorbid conditions in its guideline and the Society of Developmental and Behavioral Pediatrics recently developed a complex ADHD guideline.
· The European ADHD Guideline Group recently developed a guideline for managing ADHD during the coronavirus disease 2019 pandemic.
Perspective
Neurology
How can pediatricians treat neurodevelopmental disorders
Young-Hoon Kim
Clin Exp Pediatr. 2021;64(1):1-2.   Published online July 27, 2020
∙ Recently neurodevelopmental therapy for preschool-aged children with neurodevelopmental disorders is paid for by health insurance in Korea.
∙ There are good evidences that parenting programs and neurodevelopmental therapy can work in attention deficit hyperactivity disorder and autism spectrum disorder.
∙ Pediatricians must be able to pass away important information to parents.
Original Article
Articulation error of children with adenoid hypertrophy
Tae-Hoon Eom, Eun-Sil Jang, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee
Clin Exp Pediatr. 2014;57(7):323-328.   Published online July 23, 2014
Purpose

Adenoid hypertrophy is a physical alteration that may affect speech, and a speech disorder can have other negative effects on a child's life. Airway obstruction leads to constricted oral breathing and causes postural alterations of several oro-facial structures, including the mouth, tongue, and hyoid bone. The postural modifications may affect several aspects of speech production.

Methods

In this study, we compared articulation...

Editorial
Head circumference alone at birth, is it practical?
Young-Hoon Kim
Clin Exp Pediatr. 2014;57(2):72-74.   Published online February 24, 2014
Original Article
The effects of high-dose intravenous immunoglobulin on plasma protein and lipid levels in the patients with Kawasaki disease
Keun Young Lee, Dong-Un Kim, Hyun Seung Lee, Pil Sang Jang, Young-Hoon Kim, Jin Tack Kim, Hyun Hee Kim, Kyung-Yil Lee, Joon-Sung Lee
Clin Exp Pediatr. 2006;49(12):1348-1353.   Published online December 15, 2006
Purpose : The reticuloendothelial system is composed of sinusoidal capillaries, through which even large protein molecules are freely movable between plasma and interstitial space, including the lymphatic system. Therefore, high-dose intravenous immunoglobulin (IVIG) would cause a redistribution of proteins between two compartments. To investigate this hypothesis, we measured plasma protein and lipid levels in patients with Kawasaki disease before and...
The Therapeutic Effect of Lactobacillus reuteri in Acute Diarrhea in Infants and Toddlers
Tae-Hun Eom, Eun-Young Oh, Young-Hoon Kim, Hyun-Seung Lee, Pil Sang Jang, Dong-Un Kim, Jin-Tack Kim, Byung-Churl Lee
Clin Exp Pediatr. 2005;48(9):986-990.   Published online September 15, 2005
Purpose : Certain strains of lactobacilli are known to accelerate recovery from acute diarrhea. Lactobacillus reuteri is isolated from human breast milk and a commonly occurring Lactobacillus species with therapeutic potential in acute diarrhea. The purpose of the present study was to investigate the therapeutic effect of L. reuteri in acute diarrhea in young children. Methods : Fifty patients between...
The Efficacy of Speech and Language Therapy for Children with Speech and Language Delays according to the Eiologies
June-Bum Kim, Jin-Soon Suh, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee, Kyung-Tai Whang, Byung-Churl Lee
Clin Exp Pediatr. 2005;48(9):924-928.   Published online September 15, 2005
Purpose : Treatment efficacy for children with speech and language delay has been the subject of considerable debate in recent years. We evaluated the clinical features of children with delayed speech and language and their prognoses according to their etiologies after 6 months of speech and language therapy. Methods : From January, 2000 to March, 2004, we retrospectively reviewed 56...
The Morphologic Changes of Parvalbumin- Immunoreactive Interneurons of the Dentate Gyrus in Kainate-Treated Mouse Hippocampal Slice Culture Epilepsy Model
Hee Sun Chung, Mi-Young Shin, Young-Hoon Kim, In-Goo Lee, Kyung-Tai Whang, Myung-Suk Kim
Clin Exp Pediatr. 2002;45(12):1551-1558.   Published online December 15, 2002
Purpose : Loss of hippocampal interneurons in dentate gyrus has been reported in patients with severe temporal lobe epilepsy and in animals treated with kainic acid(KA). Interneurons contain Ca2+- binding protein parvalbumin(PV). The effects of kainic acid on parvalbumin-immunoreactive (PV-IR) interneurons in dentate gyrus were investigated in organotypic hippocampal slice cultures. Methods : Cultured hippocampal slices from postnatal day nine...
Erratum
A Case of Duplication 9p Syndrome(Partial Trisomy 9p)
Me Gyoung Lee, Young-Nae Roh, Young-Hoon Kim, Chung Sun Baek, Me Gyoung Sin, Jin Lee, Pil-Sang Jang, Jin-Tack Kim, Kweon-Haeng Lee, Kyung-Tai Whang
Accepted January 1, 1970  
Trisomy 9p syndrome was first described by Rethore, et al in 1970 and about 150 cases have been reported. Trisomy 9p has been reported as either partial or complete. The term "duplication 9p syndrome" instead of "trisomy 9p syndrome" is used since most of the reported patients had only partial duplication rather than the whole arm duplication of 9p. Duplication...
Case Report
A Case of Hereditary Motor and Sensory Neuropathy Type III
Su Hyun Cho, Soo-Jin Kim, Young-Hoon Kim, Yun Tae Kim, Yoon-Kyung Lee, Dong-Un Kim, Seung-Hoon Han, Seung-Yun Chung, In-Goo Lee, Kyung-Tai Whang, Je Geun Chi
Clin Exp Pediatr. 2001;44(9):1057-1061.   Published online September 15, 2001
Hereditary motor and sensory neuropathy type III, which is also known as Dejerine-Sottas disease, is a severe demyelinating polyneuropathy which presents from birth or infancy, and is sometimes presented as a hypotonic or floppy infant. The disease is inherited autosomal recessively and includes clinical findings of generalized muscle weakness and atrophy, with the greatest severity in distal limb muscles, areflexia, and sensory loss. The...
Erratum
The Morphologic Changes of Interneuron Dendrites in Child Epilepsy Model
Young-Hoon Kim
Clin Exp Pediatr. 2001;44(3):309-315.   Published online March 15, 2001
Original Article
A Clinical Observation of Kawasaki Meningitis and Viral Meningitis
Jae-Ho Hyun, Young-Hoon Kim, Ji-Whan Han, Jong-Wan Kim, Kyung-Tai Whang
Clin Exp Pediatr. 1995;38(6):794-803.   Published online June 15, 1995
Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis. Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100...
Case Report
A Case of Late Infantile Batten's Disease
Kyung-Tae Whang, Jong-Wan Kim, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee, Je-Geun Chi
Clin Exp Pediatr. 1994;37(12):1745-1751.   Published online December 15, 1994
We experienced a case of late infantile Batten's disease in a 4-year-7-month-old boy who was admitted to child neurology service of Kangnam St. Mary's hospital for evaluation of progressive psychomotor deterioration. He was in quit normal state of development until 3 years of age when his mother first became concerned because he showed such emotional change as crying and fear. Since...