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Case Report
Successful pleurodesis with OK-432 in preterm infants with persistent pleural effusion
Jeong Eun Kim, Chul Lee, Kook In Park, Min Soo Park, Ran Namgung, In Kyu Park
Clin Exp Pediatr. 2012;55(5):177-180.   Published online May 21, 2012

OK-432 (picibanil) is an inactivated preparation of Streptococcus pyogenes that causes pleurodesis by inducing a strong inflammatory response. Intrapleural instillation of OK-432 has recently been used to successfully treat neonatal and fetal chylothorax. Here we report a trial of intrapleural instillation of OK-432 in two preterm infants who were born with hydrops fetalis and massive bilateral pleural effusion. Both cases...

Original Article
A clinical study of congenital chylothorax and octreotide therapy
Ung Geon Oh, Kyoung Eun Choi, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin
Clin Exp Pediatr. 2008;51(11):1172-1178.   Published online November 15, 2008
Purpose : Congenital chylothorax is an accumulation of lymphatic fluid within the pleural space. It is a common cause of unidentified hydrops fetalis. We examined the perinatal history, clinical manifestation, diagnosis, treatment, and outcome in 6 newborns diagnosed to have congenital chylothorax with hydrops fetalis. We also studied the effect of octreotide therapy for congenital chylothorax in relation to conservative...
Case Report
Two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy
Eun Jin Choi, Sub Lee
Clin Exp Pediatr. 2007;50(3):298-301.   Published online March 15, 2007
Chylothorax is a rare complication following cardiac surgery for congenital heart diseases. Although conservative management is successful in the majority of cases, surgical intervention is required in a refractory one. Recently, subcutaneous or intravenous infusion of octreotide has been used as a safe treatment that helps avoiding surgical intervention. Herein, we report two cases of postoperative chylothorax treated with parenteral...
A Case of Congenital Chylothorax in a Premature Infant
Su Kyeong Oh, Young Hye Jeong, Youn Jee Choi, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 2001;44(4):460-463.   Published online April 15, 2001
We experienced a case of isolated fetal pleural effusion diagnosed by antenatal ultrasonogram in the 33th week of gestational age. Chest PA at birth showed massive pleural effusion in both lungs. The serous pleural fluid changed to a milky nature after feeding so we diagnosed it as congenital chylothorax. The infant was managed by chest tube drainage, NPO & TPN...
A Case of Idiopathic Chylothorax Treated with Pleuroperitoneal Shunt
Sung Ho Jung, Dong Un Kim, Yoon Kyung Lee, Byung Joon Choi, Jin Tack Kim, Ik Jun Lee
Clin Exp Pediatr. 1999;42(5):733-737.   Published online May 15, 1999
Chylothorax is an accumulation of lymphatic fluid or chyle in the pleurual cavity resulting from a leak of the thoracic duct or one of its major divisions. If the loss of chyle persist, life threatening nutritional and immunologic deficiencies ensue. Initial conservative managements consist of tube thoracostomy drainage and dietary modification(low fat diet and total parenteral nutrition). In some refarctory...
A Case of Isolated Fetal Pleural Effusion Antenatally Diagnose
Hae Kyung Lee, Joo Tak Lee, Joon Soo Park, Young Chang Kim, Sang Chul Park, Young Hwa Kim
Clin Exp Pediatr. 1996;39(10):1469-1473.   Published online October 15, 1996
The isolated fetal pleural effusion is rare and has no other signs of fetal hydrops. Its etiology is unknown but the most common cause is congenital chylothorax. We experienced a case of fetal pleural effusion diagnosed in the 35 weeks gestational age by antenatal ultrasonogram and antenatal diagnosis allowed early therapeutic intervention such as drainage of pleural fluid immediatly after birth. We diagnosed congenital chylothorax...
Original Article
A clinical observation on chylothorax in childhood.
Mi Jin Jung, Joon Jai Kim, Young Ah Lee, Chung Il Noh, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(4):497-506.   Published online April 30, 1991
Fourteen patients who had developed a chylothorax in childhood during a ten year period, from Jan. 1979 to July 1989, were reviewed by their hospital records. The chylothoraces occurred most frequently as complications of cardiothoracic surgeries in eight patients(57%). Four cases followed extrapericardial operations such as ligation of PDA and take-down of Blalock-Taussig shunt, and four cases followed intrapericardial operations such as corrective operations...
A Case of Pulmonary Lymphangiectasis Associated with Chylothorax.
Min Hee Kim, Jae Kyoung Lee, Oh Bae Chun, Byoung Hoon Yoo, Jae Hyung Yoo
Clin Exp Pediatr. 1987;30(4):422-426.   Published online April 30, 1987
Congenital pulmonary lymphangiectasis is a rare abnormality usually becoming manifest at birth and almost invariably fatal in neonatal period or early infancy. Chylothorax is an infrequent manifestation of this disease. We report a patient with pulmonary lymphangiectasis, 3 year old male, who had been suffered from persistent respiratory distress since 7 days after birth, in whom the diagnosis was suggested by the appearance of...
Case Report
A Case of Chylous Ascites with Chylothorax.
Koae Jong Park, Sang Hyun Byun, Jeong Soon Hwang, Yong Hun Chung
Clin Exp Pediatr. 1984;27(2):174-177.   Published online February 28, 1984
The authors experienced a case of chylous ascites with chylothorax, who was 4-month-old male infant. The clinical symptoms, signs and laboratory findings were compatible with chylothorax and chylous ascites. Clinical study and review of literature were presented briefly.
A Case of Neonatal Chylothorax.
Hyung Taek Ohm, Hea Sook Kim, Myong Sook Lee, Sang II Lee, Sang wook Kim
Clin Exp Pediatr. 1983;26(4):380-385.   Published online April 30, 1983
We experienced a case of chylothorax in a 23-days-old female who was admitted to the department of pediatrics because of respiratory difficulty and poor feeding. She was born by full-term, vacuum-extractedl The 2nd stage of labor was prolorged and umbilical cord was encircled her neck at birth. Chest P-A showed massive effusion of the right lung. Milky white fluid was obtained from thoracentesis. It was...
Congenital Chylothorax.
Jong Wie Choi, Do Kwang Yun, Pyung Kil Kim, Kyung Soon Song
Clin Exp Pediatr. 1982;25(7):748-752.   Published online July 31, 1982
Chyle is the digestive product absorbed from intestinal lymphatics which the component have high concentration of triglyceride and protein. The various pathological circumstances which give rise to intrathoracic effusion of chyle are well documented and so the etiology is clearly defined in most instances. However, the occurrence of chylothorax in early infancy, in the absence of other demonstrable diseases and...
A Case of Chylothorax & Chylous Ascites.
Byung Ryong Lee, Yong Tai Suh, Hyung Suk Byun, Chull Sohn, Myung Dong Ahn
Clin Exp Pediatr. 1981;24(9):902-906.   Published online September 15, 1981
A case of chylothorax and chylous ascites in a 10-year-old female patient who was admitted to the department of pediatrics because of abdominal distension, generalized edema and anorexia for 2 months, was described. Clinical study and review of literature were presented briefly.
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