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Original Article
A Case of Doxorubicin-induced Dilated Cardiomyopathy.
Sang Young Jeong, Soo Chun Kim, Sung Ho Cha, Young Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(8):1132-1137.   Published online August 31, 1989
Doxorubicin is one of the most effective chemotherapeutic agents in the treatment of leukemia, lymphoma and various solid tumors. Because of dose-dependent degenerative cardiomyopathy, however, doxorubicin theraphy may be discontinued ineffectively early. Doxorubicin-induced conges- tive heart failure carries a very poor prognosis since it is lethal in 60% of patients. Various methods for evaluating the cardiotoxic effect have been employed such as EKG, systolic...


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