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Purpose : The immature neonatal immune system is thought to result in increased
risk of infection. Receptors for the Fcmoiety of IgG(FcγR) are important in antibodymediated
clearance of microbes by monocytes/macrophages and immune regulation in
lymphocytes. As an approach to understanding their role in neonatal life, we have compared
the constitutive expression of the three Fc receptors-FcγRI(CD64), FcγRII(CD32)
and FcγRIII(CD16)-by neonatal and adult blood monocytes... |
