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Purpose : Apoptosis is a process of active cell death which has been suggested to be part of
hippocampal cell loss caused by kainic acid(KA). Immature rats showed higher susceptibility and
mortality to KA but did not develop recurrent seizure, long term behavioral or neuropathologic
changes. We investigated whether this was due to age-dependent resistance, and elucidated the
molecular mechanics which mediate P53-induced apoptosis,... |
