• Search
  • Advanced Search

Search

  • HOME
  • Search
Original Article
General Pediatrics
Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: analysis based on the 2016–2017 Korea National Health and Nutrition Examination Survey
Jung Hyun Lee
Clin Exp Pediatr. 2019;62(8):317-323.   Published online June 24, 2019

Purpose: Investigating the prevalence of hyperuricemia and its association with metabolic syndrome (MetS) and cardiometabolic risk factors (CMRFs) in Korean children and adolescents. Methods: This cross-sectional survey used data from the 7th Korea National Health and Nutrition Examination Survey (2016–2017); 1,256 males and females aged 10–18 years were included. Hyperuricemia was defined as serum uric acid levels were >6.6 mg/dL at...
Case Report
A case of idiopathic renal hypouricemia
Moon Hee Han, Sang Uk Park, Deok-Soo Kim, Jae Won Shim, Jung Yeon Shim, Hye Lym Jung, Moon Soo Park
Clin Exp Pediatr. 2007;50(5):489-492.   Published online May 15, 2007
Idiopathic renal hypouricemia is a disorder characterized by impaired urate handling in the renal tubules. This disease usually produces no symptoms, but hematuria, uric acid nephrolithiasis or acute renal failure may develop. A defect in the SLC22A12 gene, which encodes the human urate transporter, is the known major cause of this disorder. We describe a 10-month-old boy with idiopathic renal...
A Case of Partial Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency Presenting as Uric Acid Lithiasis
Ji Hae Kim, Mi Jung Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2004;47(9):1020-1023.   Published online September 15, 2004
The deficiency of enzyme hypoxanthine-guanine phosphoribosyltransferase(HPRT) results in hyperuricemia and subsequently manifests in diverse symptoms. Lesch-Nyhan syndrome is a disorder characterized by hyperuricemia, mental retardation, choreoathetosis, spasticity and self-mutilation, resulting from complete deficiency of the enzyme, whereas partial deficiency of the enzyme shows symptoms of milder forms more often without abnormal neurologic signs. A 7-year-old boy with normal growth and...
Original Article
Renal Anomalies in Neonates with Isolated Preauricular Tags
Myung Eun Hong, Seung Taek Yoo, Eun Jung Choi, Chang Woo Lee, Seung Taek Park, Yeon Kyun Oh
Clin Exp Pediatr. 2004;47(5):532-534.   Published online May 15, 2004
Purpose : The aim of this study was to determine the role of renal ultrasonography in neonates with isolated preauricular tags. Methods : We performed a retrospective study of 10,997 newborn infants delivered from January 1995 to June 2003 in Wonkwang University Hospital. Nineteen newborns born with isolated preauricular tags were assessed for renal anomalies by performing renal ultrasonography within one...
Pharmacokinetics of Cyclosporine A and Its Therapeutic Effect in Children with Renal Diseases
Woo Sung Chun, Min-Soo Park, Jae Seung Lee, Juyun Yu, Moon Sung Park, Ki-Soo Pa
Clin Exp Pediatr. 2004;47(2):193-203.   Published online February 15, 2004
Purpose : To know the body handling properties and anti-proteinuric effect of cyclosporine A(CsA) in children with renal diseases, 34 patients with nephrotic syndrome or glomerular diseases were included to treatment trials and evaluated. Methods : Microemulsion formula CsA, 5 mg/kg/day was administered orally in two divided doses for 9.3?.6 months. Pharmacokinetic studies of CsA were done twice at beginning and...
Case Report
A Case of Lesch-Nyhan Syndrome
Joon-Sung Kim, Jae-Seung Lee, Ha-Young Noh, Byung-Ju Kim, Young-Jong Woo, Jee-Min Park, Myung-Gwan Kim, Gu-Hwan Kim, Han-Wook Yoo
Clin Exp Pediatr. 2003;46(5):505-509.   Published online May 15, 2003
Lesch-Nyhan syndrome is an X-linked recessive disorder characterized by hyperuricemia, choreoathetosis, spasticity, mental retardation, and compulsive, self-injurious behavior. This disorder results from a complete deficiency of the purine salvage enzyme, hypoxanthine-guanine phosphoribosyl transferase(HPRT). We report here on a case of Lesch-Nyhan syndrome in a 1-year, 7-month-old male who presented with frequent vomiting, failure to thrive, and developmental delay. The diagnostic...
A Case of Branchio-Oto-Renal Syndrome
Sung Kee Kim, Young Gyun Kim, Se Chang Ham, Se Wook Oh, Yong Won Park, Sang Woo Kim
Clin Exp Pediatr. 2000;43(7):983-987.   Published online July 15, 2000
Branchio-oto-renal(BOR) syndrome is an autosomal dominant disorder. The pathophysiology of this syndrome is unknown. BOR syndrome has a wide range of clinical manifestations affecting the branchial, auditory and renal systems. Associated abnormalities of the face, lacrimal duct, palate and ureters have also been described. However, the major clinical findings associated and/ or ear pits, and renal anormaly. We experienced a case of a 15-day-old male...
Original Article
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Age Related Ca, Phosphorus, Uric acid concentration in Serum & Urine and Ca/Cr ratio, Cua/Ccr & TRP
Jah In Kim, Sang Joo Han, Hong Jin Lee, Won Il Park, Kyung Ja Lee
Clin Exp Pediatr. 1996;39(10):1405-1413.   Published online October 15, 1996
Purpose : There are many methods for the evaluation of the renal function. The proximal tubule of the nephrons have a role of reabsorption of the materials such as water, electrolytes, glucose, amino acids, and small molecular weight protein through the glomerular filtration. Therefore if abnormality is in the proximal tubule, these materials can be changed both in serum & urine. It is very...
Case Report
Recurrent Hematuria due to Renal Hypouricemia
Kyu Young Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1995;38(1):129-132.   Published online January 15, 1995
A marked low concentration of serum uric acid(0.7-1.2mg/dl) was detected in a 14-year-old boy with recurrent episodes of gross hematuria. The hypouricemia accompanied with a markedly increased urinary clearance of uric acid (32.6-56.0ml/min), which was only minimally changed after both the administration of pyrazinamide, and inhibitor of the renal tubular secretion of uric acid, and the administration of probenecid, and...
Original Article
Acute Tumor Lysis Syndrome in Burkitt Lymphoma.
Dong Kyu Jin, Soo Jong Hong, Il Soo Ha, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1988;31(3):362-369.   Published online March 31, 1988
To assess the tumor lysis syndrome in Burkitt lymphoma, we analyzed the clinical and laboratory findings of 17 patients with Burkitt lymphoma who were admitted to the Department of Pediatrics, Seoul National University Hospital from January 1979 to December 1986. The acute tumor lysis syndrome was diagnosed when two of the five following metabolic abnormal- ities were met: ① hyperuricemia (≥8.0mg/dl), ② hyperphosphatemia (≥5.5 mg/dl),...
Case Report
Acute Tumor Lysis Syndrome.
Sun Oak Park, In Sil Lee, Hyp Seop Ahn, Yong Choi
Clin Exp Pediatr. 1984;27(3):303-312.   Published online March 31, 1984
To assess the incidence and the effectiveness of preventive measures for tumor lysis syndrome, we analyzed the serial electrolytes levels in leukemia (Group A, 15 patients) and in lymphoma (Group B, 8 patients) patients. The results were 1)Serum LDH were elevated in all of the patients before the chemotherapy. 2)Serum uric acid were also elevated in 8 patients (A 5, B...
A Case of Hereditary Spherocytosis.
Eui Lim Choi, Chul Hwan Park, Tae Gyu Hwang, In Soon Park, Soon Yong Lee
Clin Exp Pediatr. 1983;26(11):1120-1124.   Published online November 30, 1983
We observed a case of hereditary spherocytosis who was a 4-month-old boy with the chief complaints of jaundice and pallor. Evidence of the same disease was also found in the patient` s father who had never been symptomatic. Diagnosis was made by presence of spherocytes in peripheral blood smear, osmotic fragility- test and autohemolysis test. A brief review of literatures was made.
Original Article
Serum Levels of Protein, Urea Nitrogen, Uric Acid, Creatinine and Serum Amylase Activity in Normal School Children.
Suck Pill Cho, Byung Wha Park, Hyung Suk Byun, Kyung Reyong Huh, Chull Sohn
Clin Exp Pediatr. 1982;25(2):148-152.   Published online February 28, 1982
Protein, and essential nutrient for the growth of children, is the chief nitrogenous substant in the serum of humans. For the purpose of establishment of the normal data for evaluation of nitrogen balance, we examined the serum levels of urea nitrogen, creatinine, uric acid and serum amylase activity as well as that of protein in 560 normal school children. The...
  • PubMed Central
  • PubMed
  • Scopus
  • Directory of Open Access Journals (DOAJ)