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Clinical Note
Allergy
Complement 4 levels of a 4-year-old girl with angioedema
Soyoung Shin, Yoon Tae Lee, Kyung Yil Lee, Joonhong Park, Jae Ho Lee, Eun Ae Yang
Clin Exp Pediatr. 2020;63(1):30-31.   Published online November 8, 2019
Original Article
Cardiology
Prediction of nonresponsiveness to medium-dose intravenous immunoglobulin (1 g/kg) treatment: an effective and safe schedule of acute treatment for Kawasaki disease
Kyung Pil Moon, Beom Joon Kim, Kyu Jin Lee, Jin Hee Oh, Ji Whan Han, Kyung Yil Lee, Soon Ju Lee
Clin Exp Pediatr. 2016;59(4):178-182.   Published online April 30, 2016
Purpose

Medium-dose (1 g/kg) intravenous immunoglobulin (IVIG) is effective in the majority of patients with Kawasaki disease (KD) but some patients who do not respond to medium-dose IVIG are at high risk for the development of coronary artery lesions (CALs). The purpose of this study was to identify the clinical predictors associated with unresponsiveness to medium-dose IVIG and the development of...

Usefulness of anterior uveitis as an additional tool for diagnosing incomplete Kawasaki disease
Kyu Jin Lee, Hyo Jin Kim, Min Jae Kim, Ji Hong Yoon, Eun Jung Lee, Jae Young Lee, Jin Hee Oh, Soon Ju Lee, Kyung Yil Lee, Ji Whan Han
Clin Exp Pediatr. 2016;59(4):174-177.   Published online April 30, 2016
Purpose

There are no specific tests for diagnosing Kawasaki disease (KD). Additional diagnostic criteria are needed to prevent the delayed diagnosis of incomplete Kawasaki disease (IKD). This study compared the frequency of coronary artery lesions (CALs) in IKD patients with and without anterior uveitis (AU) and elucidated whether the finding of AU supported the diagnosis of IKD.

Methods

This study enrolled patients diagnosed...

Case Report
A case of congenital syphilis mistaken for possible child abuse
Soon Ju Kim, Seung Woo Lee, Jung Woo Rhim, You Sook Youn, Jun Sung Lee, Kyung Yil Lee, Ja Young Hwang
Clin Exp Pediatr. 2009;52(6):710-712.   Published online June 15, 2009
We describe the case of a 4-month-old male infant diagnosed with early congenital syphilis during evaluation of a left distal humerus fracture. This report emphasizes the importance of screening for syphilis among pregnant women and newborns, and is a reminder of the continued existence of congenital syphilis.
A Case of Diffuse Panbronchiolitis Developing in Childhood
Jung Hoon You, Hyung Shin Lee, Kyung Yil Lee, Ja Hyun Hong, Mi Hee Lee, Byung Cheol Lee
Clin Exp Pediatr. 2005;48(1):97-100.   Published online January 15, 2005
Diffuse panbronchiolitis(DPB) is a chronic inflammatory airway disease predominantly affecting respiratory bronchioles, with distinct clinicopathological profiles. It was first described in 1966 by Yamanaka et al. The etiology of DPB is not yet clear, and the natural history of the disease is respiratory failure leading to cor pulmonale and ultimately death. But the long-term use of low-dose macrolide has proven...
Original Article
Penicillin Resistant Distribution and in-vitro Susceptibility of Oral Antibiotics against Streptococcus pneumoniae, isolated from Pediatric Patients with Community- Acquired Respiratory Infections in Korea
Jin Han Kang, Sun Mi Kim, Jong Hyun Kim, Hur Jae Kyun, Kyung Yil Lee, Young Ku Shin, Su Eun Park, Sang Hyuk Ma, Young Jin Hong
Clin Exp Pediatr. 2005;48(1):40-47.   Published online January 15, 2005
Purpose : S. pneumoniae is one of major pathogens of community-acquired respiratory infections. The rate of antibiotic resistance to this organism has increased, and resistance to multiple antimicrobial agents in a single strain of S. pneumoniae may compromise the efficacy of empiric antimicrobial treatment commonly used for respiratory infections. We did this study to find out the penicillin resistant distributions...
The Effects of Intravenous Immunoglobulin(IVIG) and Methylprednisolone on the mRNAs Expressions of VEGF, VCAM-1 and IL-1β of Human Umbilical Vein Endothelial Cells(HUVEC) Stimulated by IL-1β
Soh Yeon Kim, Sun Jeong Lim, Ji Whan Han, Kyung Yil Lee, Joon Sung Lee
Clin Exp Pediatr. 2004;47(12):1325-1333.   Published online December 15, 2004
Purpose : Kawasaki disease(KD) manifests a systemic vasculitis of unknown etiology in young children. Vascular endothelial growth factor(VEGF), vascular cell adhesion molecule-1(VCAM-1) and interleukin-1 beta(IL-1β) may play important roles in the pathogenesis of KD. Intravenous immunoglobulin(IVIG) and methylprednisolone(MP) are therapeutically effective for KD, however, the precise mechanisms of the two drugs are still unknown. We investigated the therapeutic efficacy of...
Epidemiological Study of Pneumococcal Nasal Carriage and Serotypes Among Korean Children
Sun Mi Kim, Jae Kyun Hur, Kyung Yil Lee, Young Kil Shin, Su Eun Park, Sang Hyuk Ma, Ahn Youn Min, Jin Han Kang
Clin Exp Pediatr. 2004;47(6):611-616.   Published online June 15, 2004
Purpose : The aim of this study was to determine the prevalence of pneumococcal nasal carriage and confirm the distribution of pneumococcal capsular serotypes in Korean children below aged 5 years old. Another reason this study was performed was to identify the theoretical coverage by seven valent conjugate pneumococcal vaccine, and confirm the penicillin resistant rate. Methods : This study included...
A Clinical Study of Tsutsugamushi Disease in Children
Jee Yeon Song, Ji Whan Han, Sung Soo Hwang, Kyung Yil Lee, Kyong Soo Lee
Clin Exp Pediatr. 1995;38(5):641-648.   Published online May 15, 1995
Purpose : Recently in Korea, there has been an increasing concern regarding Tsutsugamus-hi disease. This disease is increasingly reported in children. The purpose of this study was to c-onsider the possibility that Tsutsugamushi disease may be diagnosed as eruptive disease or F UO( fever of unknown origin) Methods : We reviewed 17 clinically or serologically confirmed cases of Tsutsugamushi dis-ease from...
High-Dose Intravenous Immune Globulin Therapy for Hyperbilirubinemia Caused by ABO Incompatibility
Dong Sung Kim, Dong Un Kim, Ji Whan Han, Sung Soo Whang, Kyung Yil Lee, Man Kyu Yang
Clin Exp Pediatr. 1993;36(8):1073-1079.   Published online August 15, 1993
Four newborn infants with hyperbilirubinemia, caused by ABO blood group incompatibility, were treated with high-dose intravenous immune globulin (IVIG). As soon as the diagnosis was clinically suspected, these infants received conventional treatment including phototherapy and were monitored closely for bilirubin levels. When bilirubin concentrations reached the risk point in spite of pjototherapy, IVIG was given at a dose of 1g/kg for...
Case Report
A Case of Intestinal Necrosis Associated with Henoch-Schönlein Purpura
Soo Jung Lee, Young Yoo Kim, Sung Soo Whang, Kyung Yil Lee, Won Ik Lee, Jeong Soo Kim, Chang Joon Ahn, Mi Kyung Jee
Clin Exp Pediatr. 1992;35(9):1291-1297.   Published online September 15, 1992
Gastrointestinal symptoms of Henoch-Schönlein commonly present abdominal pain, nausea, nomitting, melena and hematemesis and resolve mostly without any complications. Some times life threatening gastrointestinal manifestations such as massive hemorrhage, intussusception, intestinal necrosis and perforation may develop We report a case of the Henoch-Schönlein purpura with intestinal lesion in 11 year female patient who presented with colicky abdominal pain and bloody stool...
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