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Volume 44(7); Jul 2001
Clinical Lecture
Guideline for the Management of Childhood Asthma
Bok Yang Pyun
J Korean Pediatr Soc. 2001;44(7):727-731.   Published online July 15, 2001
Original Articles
Clinical Manifestations of Group A β-Hemolytic Streptococcal Pharyngits and Usefulness of Rapid Antigen Test
Youn Jeong Shin, Seong Hee Jang, Eun Sil Dong, Young Min Ahn, Myung Suk Ku
J Korean Pediatr Soc. 2001;44(7):732-741.   Published online July 15, 2001
Purpose : Accurate diagnosis of group A streptococcal(GAS) pharyngitis and appropriate antimicrobial therapy are important, particularly to prevent nonsuppurative sequelae and to reduce the improper use of antibiotics. Because the clinical presentation of pharyngitis does not reliably predict the etiologic agent, when GAS infection is suspected, diagnosis should be based on the result of a throat swab culture or antigen-detection...
Study on Hepatitis B Virus Pre-S/S Gene Mutations in Children with Chronic Hepatitis B Infection
Byeong Hee Son, Yeong Hong Park, Woo Yeong Chung
J Korean Pediatr Soc. 2001;44(7):741-751.   Published online July 15, 2001
Purpose : Hepatitis B virus(HBV) with various mutations has been reported. The aims of this study were to investigate the frequency and manifestation of HBV pre-S/S mutations in children with chronic hepatitis B infection. Methods : Sera from 17 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Seventeen...
Colonic Transit Time in Chronic Constipated Patients
Je Eun Choi, Im Jeong Choi, Jung A Lee, Sung Mi Kim, Jin Hwa Jeong, Jeong Ho Lee
J Korean Pediatr Soc. 2001;44(7):752-757.   Published online July 15, 2001
Purpose : In most instances, constipation is considered as idiopathic or functional. The total colonic transit time, traced by radio-opaque markers, makes possible the identification of the colon segment that has the motility alteration that causes constipation. We measured the total and segmental colonic transit time in children with chronic idiopathic constipation and compared the results with those without constipation...
Clinical Features of Food Protein-Induced Enterocolitis Syndrome
Jeong Sik Seo, Hai Lee Chung
J Korean Pediatr Soc. 2001;44(7):758-763.   Published online July 15, 2001
Purpose : Food protein-induced enterocolitis syndrome(FPIES) is a symptom complex of severe vomiting and diarrhea which is known as a food-related gastrointestinal hypersensitivity disorder without evidence of IgE-mediated sensitivity. We described the clinical characteristics of FPIES in young infants. Methods : Twenty-eight patients, aged 7 to 120 days, were included who were diagnosed as FPIES by clinical criteria and food challenges....
Effect of Vitamin E on Cerebral Hypoxia-Ischemia in Neonatal Rats
Jung Eun Seok, Yeon Kyun Oh, Seung Taek Park
J Korean Pediatr Soc. 2001;44(7):764-772.   Published online July 15, 2001
Purpose : In order to evaluate the hypoxia-ischemia induced neurotoxic effect and the protective effect of vitamin E as an antioxidant, cell number and cell viability were measured in cerebral neurons and astrocytes derived in neonatal rats. Methods : 7-day old neonatal rats were subjected to unilateral common carotid artery occlusion, and exposed to hypoxic condition for 3 hours. The protective...
The Effectiveness of Propofol on Pediatric Cardiac Catheterization and Electrophysiologic Study
Woo Saeng Park, Myung Chul Hyun
J Korean Pediatr Soc. 2001;44(7):773-777.   Published online July 15, 2001
Purpose : Our purpose was to evaluate the effectiveness of propofol on pediatric cardiac catheterization or radiofrequency catheter ablation. Methods : We measured the serial changes of arterial oxygen saturation, heart rate, systolic and diastolic blood pressure at 4 stages, a baseline(during normal sleep), stage 1(just after loading of propofol 2 mg/kg over 10 minutes), stage 2(10-15 minutes after propofol continuous...
The Changes of Biochemical Bone Markers in Pediatric Epileptic Children Who Received Long-term Antiepileptic Drugs and Usefullness Thereof
Eun Kyung Choi, Kyung Hee Kim, Sun Jun Kim
J Korean Pediatr Soc. 2001;44(7):778-785.   Published online July 15, 2001
Purpose : Long-term administration of anticonvulsants for pediatric epileptic patients may cause changes of bone metabolism. This study was performed to evaluate the influence of antiepileptics on the bone metabolism and growth in pediatric patients who received antiepileptics. Methods for early detection of adverse bone metabolism were also evaluated. Methods : Forty-eight epileptic patients were enrolled in this study....
Childhood Obstructive Sleep Apnea Syndrome : Clinical and Polysomnographic Findings
Yang Jun Park, Dae Kyun Koh, Jin Hee Oh, Soo Jung Lee
J Korean Pediatr Soc. 2001;44(7):786-795.   Published online July 15, 2001
Purpose : Although pediatricians may see a lot of patients with clinically suspected obstructive sleep apnea syndrome(OSAS), the actual incidence, clinical and polysomnographic manifestations of OSAS in children have not well been recognized and reported cases are rare. The objective of this study was to evaluate the efficacy of polysomnography in the diagnosis of OSAS in children and to analyze...
IGF-I on the Expression of Gene Associated with Hypoxic Ischemic Brain Injury in the Neonatal Rats
Hyung-Shin Lee, Sang-Hyun Byun, Ren Zhe Ann, Kyu-Sang Song, Young-Ik Lee, Yoo-Jung Hahn, Yong-Hun Chung
J Korean Pediatr Soc. 2001;44(7):796-807.   Published online July 15, 2001
Purpose : To investigate the effect of intraperitoneal injection of IGF-I after hypoxic ischemic brain injury on neuronal cell necrosis, apoptosis and expression of proapoptotic and antiapoptotic proteins bax and bcl-2, respectively. Methods : The right carotid artery was cut between the double ligation. Then allowed to recover for 30 minutes followed by exposure to 8% oxygen at 37℃ for...
The Effect of Imipramine and Desmopressin for the Treatment of Enuresis in Attention Deficit Hyperactivity Disorder Children
Yong Hoon Park, Eun Sil Lee, Han Ku Moon, Hyung Bae Park
J Korean Pediatr Soc. 2001;44(7):808-816.   Published online July 15, 2001
Purpose : Attention Deficit Hyperactivity Disorder(ADHD) is one of the most common childhood psychiatric diseases and nocturnal enuresis is also a common involuntary disorder, whose symptoms can appear more than 2-3 times per month even after the age of 5. The incidence of nocturnal enuresis is believed to be increasing in ADHD patients. This study investigates the effectiveness of desmopressin...
Radiologic Findings of Hands in Turner Syndrome
Young Sim Han, Moo Young Oh, Young Joon Lee, Woo Yeong Chung
J Korean Pediatr Soc. 2001;44(7):817-822.   Published online July 15, 2001
Purposes : Radiologic findings of hands in Turner syndrome(TS) which have been reported were metacarpal sign(MS), carpal sign(CS), phalangeal sign(PS), osteopenia, and delayed bone maturation. The aim of this study is to evaluate the difference of radiologic findings in TS, idiopathic short stature(ISS), and growth hormone deficiency(GHD). Methods : Sixty girls with short stature were studied for chromosome analysis, and...
Case Reports
A Case of Aseptic Meningitis Following Administration of Intravenous Immunoglobulin in A Patient with Idiopathic Thrombocytopenic Purpura
Su Jin Kim, Ji Eun Kim, Hei Won Hwang, Ji Sun Mok, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi, Woo Taek Kim
J Korean Pediatr Soc. 2001;44(7):823-826.   Published online July 15, 2001
Intravenous immunoglobulin(IVIG) has been widely used to treat idiopathic thrombocytopenic purpura in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. This report is on an 11 year-old boy with ITP who suffered from aseptic meningitis following the administration of IVIG. He was given 1 g/kg of IVIG for 2 days, and on the fourth day...
A Case of Crossed Branch Pulmonary Arteries in Dandy-Walker Malformation
Seonyoung Kim, Dongchul Park
J Korean Pediatr Soc. 2001;44(7):827-831.   Published online July 15, 2001
Crossed pulmonary arteries is an uncommon anomaly in which the ostium of the left pulmonary artery originates superiorly and to the right of the right pulmonary artery. The pulmonary arteries then cross each other and supply their respective lungs. The recognition of this rare anomaly is important because of its association with significant cardiac and extracardiac congenital abnormalities. These congenital...
A Case of Apert's Syndrome with Encephalocele and Hypogenesis of Corpus Callosum
Min Kyoung Kwon, Ja Yun Yu, Mi Ran Kim, Kon Hee Lee, Hae Ran Lee, Kwang Nam Kim
J Korean Pediatr Soc. 2001;44(7):832-836.   Published online July 15, 2001
Apert's syndrome(acrocephalosyndactyly) is a rare congenital anomaly that is characterized by the combination of premature fusion of multiple cranial sutures primarily involving the coronal suture and severe symmetrical syndactyly of fingers and toes. Some patients of this syndrome have various abnormalities of the central nervous system. We experienced a case of Apert's syndrome with craniofacial malformations, symmetric syndactyly, occipital encephalocele...
A Case of Gastric Perforation Presenting with Secondary Localized Peritonitis Due to Bamboo in Stomach
Ji Hyoun Seo, Ji Young Hwang, Ki Su Kang, Chan-Hoo Park, Hyang-Ok Woo, Myoung Bum Choi, Hee-Shang Youn
J Korean Pediatr Soc. 2001;44(7):837-840.   Published online July 15, 2001
Perforation after foreign body ingestion is rare. We report a 25-month-old girl who was diagnosed with a stomach perforation with secondary localized peritonitis caused by long, sharp bamboo. On admission, she had abdominal pain and fever. Simple abdominal erect & supine X-ray, abdominal ultrasonogram and computed tomography scan were normal. On the 6 th hospital day, gastrofiberoscopy was performed because...
Three Cases of Acute Scrotal Disorders in the Neonate
Ja Yun Yun, Min Kyoung Kwon, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim, Ho Hyun Jeong
J Korean Pediatr Soc. 2001;44(7):841-846.   Published online July 15, 2001
Acute scrotal disorders(ASD) in neonates-especially the torsion of testes- are rare, and the clinical presentations are quite different from those of adolescents or adults. The neonates with ASD are generally afebrile and do not show typical symptoms. Early diagnosis and proper treatment of ASD are very important but the differentiation of torsion and orchitis is not easy in neonates. The...
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