• Search
  • Advanced Search

Search

  • HOME
  • Search
Case Report
A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor
Byoung Chul Kwon, Kyung Mi Shin, Sung Chul Won, Chuhl Joo Lyu, Chang Hyun Yang, Hyun Ok Kim
Clin Exp Pediatr. 2002;45(7):912-916.   Published online July 15, 2002
Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and...
A Case of Neonatal Alloimmune Thrombocytopenia Related to HLA Antibody
Mi Seon Lee, Hyeon-Soo Lee, Hyun Ok Kim
Clin Exp Pediatr. 2001;44(12):1454-1458.   Published online December 15, 2001
Neonatal alloimmune thrombocytopenia(NAIT) is a very rare disease caused by maternal alloantibodies` response to neonatal platelet antigens. Because the most common cause of NAIT is incompatibility for platelet-specific antigens, NAIT cases due to anti-HLA antibodies are very exceptional. The patient was a second born female. She had no petechia or purpura at birth. But her platelet count was 55,000/mm3 and...
Original Article
The Effects of RU 41.740, a Glycoprotein Extract from Klebsiella pneumoniae, on Peripheral Blood Mononuclear Cells
Moon Kyu Kim, Dong Soo Kim, Hyun Ok Kim
Clin Exp Pediatr. 1992;35(8):1066-1072.   Published online August 15, 1992
RU 41.740 is extract of Klebsiella pneumoniae K2O1 stain with immunomodulatory properties. It was composed of two glycoproteins, each being 31 KD and 33 KD in their molecular weight, on SDS-PAGE analysis. RU 41.740 was observed to augment cell mediated immunity of human peripheral blood mononulear cells measured by tritiated thymidine uptake method. Maximal augmentation was observed after 72 hours...