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Original Article
Comparison of a whole blood Interferon-γ assay and A tuberculin skin test for detecting latent tuberculosis infection in children
Jin-Kyong Chun, Jin-Kyong Chun, Chang Ki Kim, Chang Ki Kim, Hyun Sook Kim, Hyun Sook Kim, Ghee Young Jung, Ghee Young Jung, John A. Linton, John A. Linton, Ki Hwan Kim, Ki Hwan Kim, Taek Jin Lee, Taek Jin Lee, Ji Hyun Jeon, Ji Hyun Jeon, Dong Soo Kim, Dong Soo Kim
Clin Exp Pediatr. 2008;51(9):971-976.   Published online September 15, 2008
Purpose : Surveillance for detecting and managing latent tuberculosis infection (LTBI) is a key component of tuberculosis control. The classic surveillance tool, the tuberculin skin test (TST), may have some limitations when used in the Bacillus Calmette-Guérin (BCG)-vaccinated population. The object was to perform a blood test QuantiFERON®-TB Gold In Tube (QFT-G IT) based on the detection of interferon-γ (IFN-γ)...
Clinical characteristics and prognostic factors for survival in hemophagocytic lymphohistiocytosis
Khi Joo Kim, Ki Hwan Kim, Taek Jin Lee, Jin-Kyong Chun, Chuhl Joo Lyu, Dong Soo Kim
Clin Exp Pediatr. 2008;51(3):299-306.   Published online March 15, 2008
Purpose : Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disorder characterized by fever, splenomegaly, pancytopenia, and hemophagocytosis in the bone marrow and other tissues. In this study, we investigated the clinical manifestations and prognostic factors in patients with HLH. Methods : We retrospectively analyzed the data from 29 patients who were diagnosed whit HLH in the Severance Children's Hospital from...