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Association between maternal smoking during pregnancy and risk of bone fractures in offspring: a systematic review and meta-analysis

Erfan Ayubi, Saeid Safiri, Kamyar Mansori

Clin Exp Pediatr. 2021;64(3):96-102. Published online February 5, 2020

Web of Science 10 Crossref 10

Question: What is the effect of maternal smoking during pregnancy (MSDP) on the risk of bone fractures in the offspring?
Finding: After the adjustment for misclassification, MSDP may be associated with a 27% increased risk of bone fracture in the offspring (pooled odds ratio, 1.27; 95% confidence interval, 1.00–1.62; I²=0%; P=0.537)
Meaning: Preventive measures and health education programs should be designed and implemented to encourage women to stop smoking, especially during.

DOI: https://doi.org/10.3345/cep.2019.01466

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