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Review Article

Philadelphia chromosome-positive acute lymphoblastic leukemia in childhood

Hong Hoe Koo

Clin Exp Pediatr. 2011;54(3):106-110. Published online March 31, 2011

In pediatric patients with acute lymphoblastic leukemia (ALL), the Philadelphia chromosome translocation is uncommon, with a frequency of less than 5%. However, it is classified as a high or very high risk, and only 20-30% of Philadelphia chromosome-positive (Ph+) children with ALL are cured with chemotherapy alone. Allogeneic hematopoietic stem cell transplantation from a closely matched donor cures 60% of...

DOI: https://doi.org/10.3345/kjp.2011.54.3.106

Case Report

Two Cases of Chronic Myelocytic Leukemia.

Hye Keun Kim, Hwa Young Kim, Young Youn Choi, Soon Pal Suh, Chang Soo Park

Clin Exp Pediatr. 1983;26(2):183-187. Published online February 28, 1983

The authors experienced two cases of adult type of chronic myelocytic leukemia. We diagnosed it through the evaluation of both clinical and hematologic features, but Philadephia chromosomes were not detected. Patients had been treated with my 1 eran followed by some degree of remission. A brief review of literatures was made.

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