Clinical and Experimental Pediatrics

Original Article

Gastroenterology

Efficacy and safety of carbon dioxide versus room-air insufflation in pediatric colonoscopy: a randomized controlled trial

Ajay Aravind, Ujjal Poddar, Anshu Srivastava, Moinak Sen Sarma

Clin Exp Pediatr. 2025;68(8):594-600. Published online March 11, 2025

CO₂ insufflation has been used instead of air insufflation to reduce postprocedure pain and discomfort in adults; however, adequately powered studies in children are scarce. This randomized controlled trial of 200 children showed that CO₂ insufflation reduces postprocedure pain and discomfort during pediatric colonoscopy with no signs of CO₂ retention. CO₂ insufflation is safe and causes less pain in children.

DOI: https://doi.org/10.3345/cep.2024.02012

Clinical study of intussusception in infants and childhood.

Sang Joo Han, Yeon Sung Lim, Bae Young Kim, Won Il Park, Kung Ja Lee

Clin Exp Pediatr. 1989;32(11):1489-1495. Published online November 30, 1989

Intussusception is an invagination of a segment of the gastrointestinal tract into an adjacent segment. It is the most common cause of acquired intestinal obstruction during infancy and early childhood. We compared the results of treatment with Barium Enema in 33 cases with that of Controlled Air Insufflation in 31 cases from January, 1985 to December, 1987. The results were as follows: 1) In age incidence, 86%...

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A Clinical Observation of Intussusception in Infants and Children: Comparing the results of barium enema with that of controlled air insufflation.

Nam Heon Kim, Won A Park, In Ho Kim, Churl Young Chung, Sang Woo Kim

Clin Exp Pediatr. 1982;25(7):708-716. Published online July 31, 1982

Intussusception which is the mot frequent cause of intestinal obstrucsion in childhood, is the invagination of a segment of the gastrointestinal tract into an adjacent segment. Since 1927, barium enema under fluoscopic guidance has been used widely as a therapeutic method. In 1953, Fiorito and Cuestas reported the use of controlled insufflation of air for diagnosis and treatment of intussusception....

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