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Original Article

Characterization of B Cells of Lymph Nodes and Peripheral Blood in a Patient with Hyper IgM Syndrome

Dong Soo Kim, Kyuong Mi Shin, Woo Ick Yang, Jeon-Soo Shin, Chang Hwa Song, Eun Kyeong Jo

Clin Exp Pediatr. 2003;46(2):128-136. Published online February 15, 2003

Purpose : Hyper IgM syndrome(HIGM) is characterized by severe recurrent bacterial infections with decreased serum levels of IgG, IgA, and IgE but elevated IgM levels. Recently, it has been classified into three groups; HIGM1, HIGM2 and a rare form of HIGM. HIGM1 is a X-linked form of HIGM and has now been identified as a T-cell deficiency in which mutations...

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