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Purpose : Adrenocorticotropic Hormone(ACTH) therapy is useful in the treatment of patients with infantile spasm. However, serious side effects including Cushing syndrome, infections, hypertension, and electrolyte imbalance must be encountered. Moreover, hypertrophic cardiomyopathy in association with ACTH therapy has recently reported. We performed thiw study to evaluate the effect of ACTH on heart muscle.
Methods : We administered ACTH subcutaneously to... |