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Original Article
Study on Hepatitis B Virus Pre-S/S Gene Mutations in Children with Chronic Hepatitis B Infection
Byeong Hee Son, Yeong Hong Park, Woo Yeong Chung
Clin Exp Pediatr. 2001;44(7):741-751.   Published online July 15, 2001
Purpose : Hepatitis B virus(HBV) with various mutations has been reported. The aims of this study were to investigate the frequency and manifestation of HBV pre-S/S mutations in children with chronic hepatitis B infection. Methods : Sera from 17 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Seventeen...
Mutations in Hepatitis B Virus Precore and Core Promotor in Children with Chronic Hepatitis B Infection - Comparison Between Vertical and Non-vertical Transmission -
Jin Kuk Kim, Yeong Hong Park, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 2000;43(6):779-791.   Published online June 15, 2000
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 46 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction product of HBV DNA. In this study, the patients were divided...
Hepatitis B Virus Precore and Core Promotor Mutations in Children with Chronic Hepatitis B Infection
Woo Yeong Chung, Jin Kuk Kim, Yeong Hoon Kim, Yeong Hong Park, Chul Ho Kim
Clin Exp Pediatr. 1999;42(10):1392-1402.   Published online October 15, 1999
Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection. Methods : Sera from 31 children with chronic HBV infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Twenty-nine adr type were analyzed. The mutations...