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Original Article
Sex Hormone Binding Globulin Levels in Children with Insulin Dependent Diabetes Mellitus
Duk Hi Kim, Mi Jung Park, Ho Sung Kim
Clin Exp Pediatr. 1995;38(7):963-969.   Published online July 15, 1995
Purpose : Sex hormone binding globulin(SHBG) is produced in liver and binds to testostero-ne and estradiol. Plasma SHBG levels are increased by estrogen and thyrotoxicosis and decreased by testostrone, insulin, growth hormone, prolactin, obesity and noninsulin dependent diabetes mellitus. SHBG levels in patients with NIDDM is known to be higher than normal, but SHBG levels in children with IDDM is controversial....
Body Composition of Children and Adolescents with Insulin-dependetn Diabetes Mellitus
Hye Young Kang, Mi Jung Park, Duk Hi Kim, You Kyung Park, Jong Ho Lee, Ho Seong Kim
Clin Exp Pediatr. 1994;37(12):1709-1716.   Published online December 15, 1994
Bodycomposition measurement is useful in the diagnosis of pathoogy, assessment of disease process and response to treatment in many endoclonologic and metabolic diseases. The Techniques used currently are mostly indirect, often expensive, difficult and time-consuming. A new method for estimation of body composition, infrared interactance, is rapid, safe, noninvasive, and may be useful in research ad clinical studies. Body composition was...
A case of idiopathic precocious puberty treated with a luteinizing hormone relaeasing hormone analog.
Keun Hee Chung, Yoo Mi Kim, Mi Won Kim, Soon Ki Kim, Moon Soo Park, Jin Keun Chang
Clin Exp Pediatr. 1991;34(8):1132-1138.   Published online August 31, 1991
We experienced a 4 year girl with idiopathic precocious puberty treated with a long acting LHRH analog (Buserelin). As an indction therapy she received LHRH analog for 6 months in subcutaneous route. After then she was maintained by intranasal therapy for 6 months. One month after the induction therapy began, we observed prepunbertal pattern of LHRH stimulation test and significant suppression of 17B-estradiol level....
Adrenocortical carcinoma in a twelve month old male infant.
Woo Ryoung Lee, Kyoung Whan Oh, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(1):137-143.   Published online January 31, 1991
Adrenocortical carcinoma is a rare disease in childhood. Most of these carcinomas are functional, produc- ing endocrine abnormalities such as Cushing syndrome, virilization, precocious puberty, hyperaldosteronism or feminization. We experienced a case of adrenocortical carcinoma in a 12 month old male infant who exhibited features of Cushing syndrome, Virilization, precocious puberty and hyperaldosteronism, which were due to functional adrenocortical carcinoma. Microscopic examination revealed cellular pleomorphism...
A Case of Estrogen-producing Sertoli-Leydig Cell Tumor with Precocious puberty.
Myung Sun Oh, Nan Kyoung Kim, Dae Hyun LIm, Jeung Hee Kim, Byong Kwan Son, In Suk Joo, Ku Sang Kim, Young Chai Joo
Clin Exp Pediatr. 1990;33(9):1301-1305.   Published online September 30, 1990
We have experienced a case of estrogen producing Sertoli-Leydig cell tumor with precocious puberty in a 2-year-old girl. Her chief complaints were breast enlargement, which was noticed 20 days prior to admission and vaginal bleeding, which was noticed 10 days prior to admission. The diagnosis was made on the basis of history, physical examination, ultra sonography, hormonal study, and histologic study after operation. She was...
Study on Pubertal Changes in Adolescent Girls.
Sang Mi Ha, Ki Soo Pai, Un Jun Hyoung, Duk Hi Kim
Clin Exp Pediatr. 1990;33(7):989-998.   Published online July 31, 1990
Puberty is the period of transition from childhood to adulthood whereby rapid growth takes place psychologically and physically, especially sexual maturation. Puberty usually starts at 10 to 12 years and ends at 17 to 19 years. However due to recent improvement in general hygiene, nutrition and standard of living, puberty comes at an earlier age. Three thousand nine hundred and ninety seven girls from...
A Case of Sexual Precocity with Congenital Hypothyroidism.
Wan Kyu Lee, Eun Jun Hyung, Duk Hi Kim
Clin Exp Pediatr. 1990;33(2):259-263.   Published online February 28, 1990
Sexual precocity in assocition with congenital hypothyroidism is a rare clinical entity. We experi- enced a case of sexual precocity, such as vaginal bleeding, breast development in a patient with congenital hypothyroidism' We present with the brief review of related literature.
A Case of the Hepatoblastoma with Precocious Puberty.
In Young Park, Byung Jun Lee, Byung Churl Lee
Clin Exp Pediatr. 1989;32(5):735-740.   Published online May 31, 1989
Hepatoblastoma is a rare neoplasm in childhood. Hepatoblastoma associated with precocious puberty caused by human chorionic agonadotropin (HCG) secreted by the tumor itself, is very rare. We experiened a case of hepatoblastoma with precocious puberty in a 28-month-old boy, who was admitted because of abdominal pain, enlarged testis & penis, pubic hair and a deep voice. Diagnosis was made by typical Clinical manifestation, elevated...
A Study on Hormonal Change of Lh, FSH, and Testosterone and Testicular Volumes in Pubertal Mal Children.
Heung Dong Kim, Duk Hi Kim, Ki Keun Oh
Clin Exp Pediatr. 1986;29(9):979-987.   Published online September 30, 1986
The mechanism involved in pubertal changes has not been clearly demonstrated, but evidence has been accumulated that hormonal changes are responsible for this pubertal changes. We studied the height, weight, testicular volume, bone age, LH, FSH, and testosterone, "by Tanner stage of pubic hair development in 134 pubertal male children with no previous endocrine disease, who admitted at Yonsei University Medical...
Case Report
A Case of Precocious Pseudopuberty due to Granulosa Cell Tumor in an Infant.
Young Ran Choi, Youn Ha Kang, Kyo Sun Kim, Chang Hyo Lee
Clin Exp Pediatr. 1983;26(8):835-839.   Published online August 31, 1983
We have experienced a case of precocious psevdopuberty due to granulosa cell tumor in a female infant, aged 11 months. She had whitish vaginal discharge and two episcdes of vaginal bleedirg one month apart. The breasts were markedly enlarged for her age but pubic ard axillary hair were not noticed. Recto abdominal examination revealed a firm, adult wrist sized, globular mass,...