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Original Article
The Therapeutic Effects of Dexamethasone in Bronchopulmonary Dysplasia
Min Joong Kwon, Kook In Park, Min Soo Park, Ran Namgung, Chul Lee, Dong Kwan Han
Clin Exp Pediatr. 1993;36(12):1672-1680.   Published online December 15, 1993
We observed clinical features of 18 bronchopulmonary dysplasia (BPD) patients who were admitted to the neonatal intensive care unit in the Severance Hospital of Yonsei University College of Medicine from January 1. 1987 to June 30. 1991. Eight patients in whom ventilator settings were unchanged from for more than 5 days because of lack of improvement in pulmonary function. ...
Case Report
A Case of Primary Pulmonary Hypertension
Sang Woo Lew, Hae Yong Lee, Hwang Min Kim, Jae Seung Yang, Jong Soo Kim
Clin Exp Pediatr. 1993;36(10):1452-1457.   Published online October 15, 1993
We have experienced a 14 year old female patient who had suffered from headache, dizziness, exertional dyspnea and chest pain during 6 months. She was diagnosed as primary pulmonary hypertension by ultrasonogram and cardiac catheterization. On the cardiac catheterization, there was elevated pulmonary artery pressure and normal pulmonary wedge pressure. We report this case with related literature review.
Original Article
The Relationship between Spontaneous Diuresis and Changes of Pulmonary Function in Infants with Respiratory Distress Syndrome
Byeong Hyun Kim, Jae Kag Choi, Yeon Kyun Oh, Kwang Soo Oh, Hyang Suk Yoon, Chong Cuk Kim
Clin Exp Pediatr. 1993;36(8):1094-1100.   Published online August 15, 1993
To evaluate the relationship between spontaneous diuresis and improvement of pulmonary function in respiratory distress syndrome, 15 premature neonates requiring mechanical ventilation for RDS, who admitted in NICU of Wonkwang University Hospital from January 1990 to June 1992, were studied. The results were as follows(results are mean¡¾SEM) 1) Mean birth weight of study infants was 1.82¡¾0.08Kg, and mean gestational age was 32.80¡¾0.54...
Normal Predicted Values of Pulmonary Function Test Korean School-Aged Children
Kyung Ae Yoon, Hyung Suk Lim, Young Yull Koh, Heon Kim
Clin Exp Pediatr. 1993;36(1):25-37.   Published online January 15, 1993
In recent years pulmonary function tests have had a wide application in clinical pulmonary diseases. By combining a number of different pulmonary function tests, abnormality present in a particular patient can be defined. This narrows the list of possible diagnosis and allows to determine accurately the degree of impairment and assess the response to therapy. To assess the pulmonary function in...
A Cause of Transient Systolic Murmur in Neonates Physiologic Pulmonary Artery Stenosis
Hyun Joo Kwak, Phil Seob Sim, Kwang Chul Lee, Chang Sung Sohn, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1992;35(12):1696-1701.   Published online December 15, 1992
A transient heart murmur is frequently heard in normal newborn who has no congenital heart disease. The cause of this murmur remains unclear but was speculated as hypoplasia of the pulmonary arterial branches or unusual alignment of the main pulmonary artery with its branches. Pulsed Doppler and two-dimensional echocardiographic studies were undertaken in 19 newborn infants with a transient murmur and...
Case Report
A Case of Right Pulmonary Artery Arising from Ascending Aorta
Chan Uhng Joo, Nam Ki Kim, Ja Hong Kuk, Doing Geun Lee
Clin Exp Pediatr. 1992;35(9):1303-1306.   Published online September 15, 1992
The anomaly consisting of one pulmonary artery arising from the ascending aorta while the other originates normally from the right ventricle is a rare congenital malformation. Early surgery is desirable to prevent pulmonary vascular obstructive disease. The autoors experienced a patient of right pulmonary artery arising from ascending aorta who had severe respiratory distress. Echocardiographic study and autopsy findings showed anomalous...
Two Cases of Anomalous Origin of the Right Pulmonary Artery from the Ascending Aorta
Yong Won Park, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim, Joon Ryang Rho, Kyung Pil Suh
Clin Exp Pediatr. 1992;35(7):995-1000.   Published online July 15, 1992
Anomalous origin of the pulmonary artery from the ascending aorta is a rare congenital cardiovascular anomaly which usually involves the right pulmonary artery. Because congestive heart failure and the pulmonary vascular obstructive changes develop early in life, early diagnosis and surgical correction are essential. We experienced two cases of anomalous origin of the right pulmonry artery from the ascending aorta; aorticopulmonary septal...
A Case of Unilateral Absence of Pulmonary Artery
Joon Ho Bang, Sang Nyen Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(6):873-878.   Published online June 15, 1992
A Unilateral Absence of Pulmonary Artery(UAPA), which develops occasionally as one of the associated anomaly in congenital cardiovascular defect like as tetralogy of Fallot, is rare anomaly as an isolated congenital defect. We have recently experienced a case of UAPA in a 9 years old boy, which was diagnosed by perfusion scan, digital subtraction angiography. So we report this case...
Two Cases of Idiopathic Pulmonary Fibrosis
Young Gyun Oh, Seoung Hwan Kim, Mi Reong Kim, Byung Kiu Park, Hee-Shang Youn, Myung Kul Yum
Clin Exp Pediatr. 1992;35(1):122-128.   Published online January 15, 1992
Idiopathic pulmonary fibrosis is a heterogeneous group of disorder which predominantly affects the lung parenchyma and spares the airway. We report two cases of idiopathic pulmonary fibrosis in a 2 year 11 month-old female and a 1 year 1 month-old male patients who were treated with steroid. These patients presented with dyspnea and showed fine crepitant rales in both lung...
Original Article
A Scientific Analysis of Changes in Hemostatic Parameters Following Cardiopulmonary
Hyoung Won Lee, You In Park, Kwang Chul Lee, Ju Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1992;35(1):34-43.   Published online January 15, 1992
Despite the scientific advances made in medical science, the potential for serious hemorrhagic complications remain an important problem in patients undergoing open heart surgery with extracorporeal circultation (OHSEC). Hematologic abnormalities that have been reported in association with OHSEC and that may lead to a hemorrhagic tendency include thrombocytopenia, alteration of coagulation factors, advanced fibrinolysis and inadequate neutralization of heparin. We investigated...
Three cases of Watson-Alagille syndrome.
Eun Kyeong Bom, Dae Hyun Kim, Dong Hoon Koh, Young Youn Choi, Jae Sook Ma, Tae Ju Hwang
Clin Exp Pediatr. 1991;34(12):1699-1706.   Published online December 31, 1991
Watson-Alagille syndrome is a kind of familial intrahepatic biliary atresia associated with charac- teristic face and cardiovascular anomaly. Growth and developmental delay, anomalies of the eyes such as posterior embryotoxon, deformities of the skeletal system are often the manifestations of this syndrome. We experienced three cases of Watson-Alagille syndrome recently. These patients showed charac- teristic faces and had peripheral pulmonary artery stenosis diagnosed by pulmonary...
Congenital cystic diseases of the lung.
Won Soon Park, Young Pyo Chang, Hee Ju Kim, Young Yull Koh, Jung Hwan Choi, Chong Ku Yun, Joo Hyun Kim
Clin Exp Pediatr. 1991;34(12):1671-1677.   Published online December 31, 1991
Congenital cystic diseases of the lung (CCDL) is a clinical group of disorders characterized by a cystic appearance of pulmonary tissue. It can be classified into four distinct categories: 1) Congenital lobar emphysema (CLE), 2) Congenital cystic adenomatoid malformation (CCAM), 3) Pulmonary sequeestration (PS), and ^Bronchogenic cyst (BC). 24 patients with CCDL admitted to the Seoul National University Children’s Hospital from January 1984 to June...
A case of pulmonary vascular air embolism in the newborn.
Won Soon Park, Beom Soo Park, Hye Kyung Han, Jung Hwan Choi, Chong Ku Yun, Kyoung Mo Yeon, Je Geun Chi
Clin Exp Pediatr. 1991;34(10):1422-1427.   Published online October 31, 1991
Pulmonary vascular air embolism is a rare, and almost invariably fatal complication of positive pressure ventilation of newborn infants. There have only been 53 cases described in the world literature to date. We have experienced a case of pulmonary vascular air embolism in a premature newborn as a complication of mechanical ventilation during the course of respiratory distress syndrome. The pathophysiology and clinical characteristics of...
Tricuspid atresia associated with double orifice mitral valve and coronary sinus septal defect.
In Sook Park, Ki Soo Kim, Young Seo Park, Chang Yee Hong, Shi Joon Yoo, Meong Gun Song
Clin Exp Pediatr. 1991;34(8):1139-1145.   Published online August 31, 1991
Clinical, echocardiographic and angiographic findings of a very rare case of cardiac malformation is presented. The main features were tricuspid atresia, coronary sinus septal defect, and double orifice mitral valve. These defects were correctly diagnosed by echocardiography and were confirmed by angiocardiography. This patient was palliated successfully with blade balloon atrial septostomy and bidirectional cavopulmonary shunt. To the best of our knowledge, this is the...
The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.
Eun Ae Park, Yung Sook Ko, Gyoung Hee Kim
Clin Exp Pediatr. 1991;34(8):1086-1092.   Published online August 31, 1991
The purpose of this study was to determine the relationship between improvement of pulmonary, function and diuresis in respiratory distress syndrome. This study was based on 24 cases of RDS infants admitted in NICU of Ewha Womans University from January 1988 to December 1990. The results were as follows. 1) Mean birth weight of study cases was 2.11 kg with gestational age between 29〜39 weeks. 2) Maximum...
Pulsed doppler echocardiographic analysis of pulmonary venous flow in congenital heart diseases with left-to-right shunt.
Kye Hwan Seol, Chang Sung Son, Joo Won Lee, Soon Kyum Kim, Young Chang Tockgo
Clin Exp Pediatr. 1991;34(7):934-939.   Published online July 31, 1991
Pulsed Doppler echocardiography was performed to evaluate the flow velocity pattern of the pulmonary vein in 28 patients with congenital heart diseases which comprised of 8 atrial septal defect (ASD), 14 ventricular septal defect (VSD) and 6 patent ductus arteriosus (PDA). 20 normal children served as controls. The objective of this study was to ascertain that pulmonary venous flow velocity is dependent on the...
Relationship between underlying disease and time at onset of neonatal pulmonary air leak.
Young Yaek Jang, Kyong Nyong Kim, Jong Lim Choi, Ok Kyung Lee
Clin Exp Pediatr. 1991;34(7):921-928.   Published online July 31, 1991
We observed 38 cases of neonatal pulmonary air leak who were admitted to the nicu of Presbyter- ian Medical center from July, 1984 to October, 1990. The result was as follows: 1) The overall incidence of neonatal pulmonary air leak was 0.15% of all live birth. Spontaneous pulmonary air leak were 6cases (0.03%) and secondary pulmonary air leak were 21 cases (0.12%). 2) There were no differences...
A case of pneumoperitoneum secondary to pulmonary airleak and a similar case of abdominal subcutaneous emphysema.
Sei Joong Ko, Moon Chul Kim, Jai Eok Kim
Clin Exp Pediatr. 1991;34(6):837-842.   Published online June 30, 1991
Pneumoperitoneum in association with pulmonry airleak syndrome is rarely encountered in spite of the rather frequent occurence of the pulmonary airleak syndrome in the neonates and the premature babies under ventilator therapy. In most cases of pneiimoperitoneum, the major cause is gastrointes- tinal perforation which evidently requires emergency surgery. Nevertheless, no such aggressive procedure as explolaparotomy is needed in case of pneumoperitoneum secondary to...
Acute hemodynamic effects of increasing hemoglobin concentration in children with congenital heart disease and relative anemia.
You In Park, Young You, Chang Sung Son, Joo Won Lee, Young Chang Tocko
Clin Exp Pediatr. 1991;34(6):787-795.   Published online June 30, 1991
The short-term effects of increasing hemoglobin concentration were evaluated on cardiac catheter- ization in nine patients with congenital heart diseases and relative anemia. Diagnosis were ventricular septal defect in six, tetralogy of Fallot in two, and endocardial cushion defect in one. Various hemodynamic data including pulmonary and systemic blood flow, pulmonary and systemic vascular resistance and the degree of shunt were compared before and...
Percutaneous transluminal balloon valvuloplasty for congenital pulmonary valvular stenosis.
Sung Min Choi, Sang Bum Lee, Doo Hong Ahn, Yong Joo Kim
Clin Exp Pediatr. 1991;34(3):311-316.   Published online March 31, 1991
Congenital pulmonary valvular stenosis was relieved by percutaneous balloon valvuloplasty during cardiac catheterization on 8 children aged 14 months to 8 years. Before dilatation, the transpulmonary systolic pressure gradients ranged from 33 mmHg to 79 mmHg (Mean:52.00 ± 18.16 mmHg). There were significant reduction in the transpulmonic systolic pressure gradients immediate after balloon dilatation (Mean:17.38±11.16mmHg). In follow up 4 patients, this decreased pressure gradients have...
A case of interstitial pulmonary fibrosis.
Hak Won Kim, Ho Joon Im, In Joon Seol, Ha Baik Lee, Hahng Lee, Seok Chol Jeon, Moon Hyang Park
Clin Exp Pediatr. 1991;34(1):107-114.   Published online January 31, 1991
Interstitial pulmonary fibrosis is a rare, diffuse lug disease which has a tendency to destroy the lung architectures by consequent healing with progressively severe fibrosis. We report with a brief review of literature, one case of a 7-year old female with the typical pictures of interstitial pulmonary fibrosis, histologically on open lung biopsy, and clinically presenting with chronic respiratory difficulty but without definite symptoms...
Changes of PPD-Specific Immunoglobulin in Pulmonary Tuberculosis After Treatment.
Ja Young Kim, Mun Hwan Lee, Pyoung Han Hwang, Chan Uhng Joo, Jung Soo Kim
Clin Exp Pediatr. 1990;33(12):1647-1655.   Published online December 31, 1990
The definite diagnosis and precise assessment of response to therapy is still a problem in childhood tuberculosis because these patients rarely produce sputum and if obtained it may be negative. For this reason, diagnosis rely largely on the clinical and X-ray examination, which have a low specificity and high proportion of false positive results. Recently immunologic diagnosis of tuberculosis using enzyme-linked immunosorbent assay (ELISA) was...
A Case of Pulmonary Blastoma.
Kang Seo Park, Kyu Sun Choi, Kyong Nyong Kim, Wan Soeb Kim, Kwang Min Lee, Dong Kyu Chung
Clin Exp Pediatr. 1990;33(10):1447-1453.   Published online October 31, 1990
Pulmonary blastoma is a rare primary lung tumor consisting of a mixture of blastomatous and immature-looking epithelial and mesenchymal components. The histogenesis is not clarified. This disease is first described by Barnard in 1952 as “embryoma of lung” because of its resemblance to fetal lungs. In 1961, Spencer reported three new cases and suggested the name ^pulmonary blastoma” because of the resemblance to nephroblastoma...
Studies on the Change of Pulmonary Artery Pressure in Early Neonatal Period.
Jung Ae Kim, Yung Kyun Oh, Byung Kiu Park, Hee Shang Youn, Myung Kul Yum
Clin Exp Pediatr. 1990;33(8):1081-1086.   Published online August 31, 1990
The change of postnatal pulmonary artery pressure was studied with doppler echocardiography and phonocardiogram in 40 normal full term neonates before 6 hours, between 6 〜 24 hours, 24~48 hours, 48-72 hours, 72 hours 〜 7 days. The results of study were as follows: Pc-To interval (sec) decreased (0. 071 ±0.002, 0.062±0.003, 0.050±0.002, 0.037±0.007, 0.027±0.003) and AT/ET ratio increased (0. 24±0.01, 0.30±0.02, 0.40±0.03, 0.40±0.04,...
Comparisons of the Pressure Gradients between Two-Dimensional Echocardiographic Doppler Studies and Cardiac Catheterization in Pulmonary Stenosis.
Won Ho Choi, Young Sook Kang, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1990;33(7):940-945.   Published online July 31, 1990
The right ventricular outflow tract pressure gradient measured by Doppler echocardiography was compared with the pressure gradient by cardiac catheterization in 19 children who were admitted to the department of Pediatrics, Dong San Hospotal during the period of 18 months from January 1987 to June 1988 for the evaluation of heart disease. Among 19 cases, 10 cases were Tetralogy of Fallot, 5 cases were...
Pulmonary Air Leaks in the Newborn.
Soon Wha Kim, Kyung Hee Kim, Young Jin Hong, Don Hee Ahn
Clin Exp Pediatr. 1990;33(7):907-914.   Published online July 31, 1990
A clinical study was performed on 26 cases of pulmonary air leaks in the newborn who were admitted to the NICU of National Medical Center from Jan. 1984 to Aug. 1988 The results were as follows: 1) Spontaneous air leaks were 2 cases (7.7%)and secondary air leaks were 24 cases (92.3%). 2) Of the 26 cases of pulmonary air leaks, 13 cases (50.0%) had meconium aspiration...
Treatment of Congenital Pulmonary Arteriovenous Fistula with Therapeutic Embolization in a Child.
Byung Hee Kim, Young Soo Chun, Jin Soo Choi, Jae Sook Ma, Tai Ju Hwang, Jae Kyu Kim
Clin Exp Pediatr. 1990;33(6):835-841.   Published online June 30, 1990
Congential pulmonary arteriovenous fistula is an uncommon malformation which has an abnormal connection between the pulmonary capillary bed, in which venous blood in the pulmonary artery is shunted through the fistula into the pulmonary vein without exposure to alveolar air, enters the left heart, and results in systemic arterial unsaturation, polycythemia, cyanosis and clubbing. Death often results from cerebral abscess and rupture of the...
The Estimation of Pressure Gradients of the various Cardiac Chambers Using Conbtinuos-Wave Doppler Echocardiography in Congenital Heart Disease.
Du Young Choi, Yeon Sim Kim, Hyung Suk Yoon
Clin Exp Pediatr. 1990;33(3):324-331.   Published online March 31, 1990
Continuous-Wave doppler echocardiography was used to estimate the Pressure gradient in 55 children with congenital heart disease. To test whether the Doppler method would be useful for evaluation and management of pediatric patients with ventricular septal defect (VSD)), pulmonic stenosis (PS), tricuspid regurgitation (TR), we recorded the maximal velocity (Vmax) of transseptal, pulmonary and regurgitant tricuspid jet flows and calculated the pressure gradients used by...
The Anatomy of Pulmonary Artery Determined by Angiography in Ventricular Septal Defect and Pulmonary Atresia.
Jung Yun Choi, Young Hwue Kim, Yong Soo Yun
Clin Exp Pediatr. 1989;32(12):1678-1685.   Published online December 31, 1989
Thirty seven cases of ventricular septal defect and pulmonary atresia in normally connected heart, diagnosed at Seoul National University Children’s Hospital from October 1987 to May 1989 were studied to determine the source of pulmonary blood flow, pulmonary artery anatomy and their sequential changes. Also was studied the relationship between major aortopulmonary collateral artery (MAPCA) and intra parenchymal pulmonary arteries and central pulmonary artery...
Factors Associated with Pneumothorax in Hyaline Membrane Disease In fants Receiving Mechanical Ventilation.
Oh Kyung Lee, Kyung Hee Kim, Kyu Sun Choi, Wan Seoub Kim
Clin Exp Pediatr. 1989;32(12):1642-1649.   Published online December 31, 1989
We observed 42 cases of neonates, who were diagnosed as having Hyaline membrane disease and had been received mechanical ventilation in neonatal intensive care unit of Presbyterian medical center from July 1984 to July 1988. In order to observe the factors associated with pneumothorax, we devide these cases in two groups. First group was consists of infants with pneumothorax, second group was consists of...