Clinical and Experimental Pediatrics

Original Article

Infection

Predicting COVID-19 transmission in a student population in Seoul, South Korea, 2020–2021

Young Hwa Lee, Han Ho Kim, Young June Choe

Clin Exp Pediatr. 2023;66(4):173-178. Published online December 22, 2022

Question: What is the spatial distribution and determinants of coronavirus disease 2019 (COVID-19) infection among students in Korea?
Finding: The community population was closely associated with the risk of COVID-19, and the number of students per school class were inversely associated with COVID-19 rates in students.
Meaning: Our finding suggests that controlling the community-level burden of COVID-19 can help prevent sudden acute respiratory syndrome coronavirus 2 infection in school-aged children.

DOI: https://doi.org/10.3345/cep.2022.00983

Clinical characteristics of pediatric patients infected with SARS-CoV-2 versus common human coronaviruses: a national multicenter study

In Suk Sol, Eun Lee, Hyeon-Jong Yang, Yong Ju Lee, Hye Yung Yum, Mi-Hee Lee, Mi Ae Chu, Hui Jeong Moon, Hyo-Bin Kim, Ju Hee Seo, Jung Yeon Shim, Ji Young Ahn, Yoon Young Jang, Hai Lee Chung, Eun Hee Chung, Kyunghoon Kim, Bong-Seong Kim, Cheol Hong Kim, Yang Park, Meeyong Shin, Kyung Suk Lee, Man Yong Han, Soo-Jong Hong, Eun Kyeong Kang, Chang Keun Kim; on behalf of The Pneumonia & Respiratory Disease Study Group of Korean Academy of Pediatric Allergy and Respiratory Disease

Clin Exp Pediatr. 2023;66(3):134-141. Published online December 22, 2022

Crossref 1

Question: The clinical differences between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and human coronaviruses (HCoV) in children remain unknown.
Finding: This study compared the clinical findings of children infected with SARS-CoV-2 versus HCoV. Its findings suggest that children and adolescents with SARS-CoV-2 have a milder clinical course than those with HCoV.
Meaning: The clinical course of children and adolescents with SARS-CoV-2 should be closely monitored during the coronavirus disease 2019 pandemic.

DOI: https://doi.org/10.3345/cep.2022.00703

Other

Clinical spectrum and short-term outcomes of multisystem inflammatory syndrome in children in a south Indian hospital

Muruganantham Balagurunathan, Thrilok Natarajan, Jothilakshmi Karthikeyan, Venkateshwaran Palanisamy

Clin Exp Pediatr. 2021;64(10):531-537. Published online August 4, 2021

Web of Science 8 Crossref 13

Question: What are the clinical spectrum, course, and short-term outcomes of multisystem inflammatory syndrome in children (MIS-C)?
Finding: MIS-C can have variable clinical manifestations. Fever is most common, followed by gastrointestinal and cardiovascular symptoms. Early identification and appropriate management lead to favorable outcomes.
Meaning: MIS-C can present in a myriad of ways and severities. High suspicion is necessary to ensure its early identification and appropriate management and favorable patient outcomes.

DOI: https://doi.org/10.3345/cep.2021.00374

Review Article

Infection

School closures during the coronavirus disease 2019 outbreak

Eun Young Cho, Young June Choe

Clin Exp Pediatr. 2021;64(7):322-327. Published online May 31, 2021

Web of Science 4 Crossref 6

· Earlier modeling studies of the effects of school closures on severe acute respiratory syndrome coronavirus 2 were largely derived from the pandemic influenza model, resulting in conflicting implications.
· Observational findings suggest no clear effect of school closures on community transmission or overall mortality.
· School closures must be weighed against potential high social costs, which can also negatively affect children’s health.

DOI: https://doi.org/10.3345/cep.2021.00353

Neonatology (Perinatology)

Clinical implications of coronavirus disease 2019 in neonates

Do-Hyun Kim

Clin Exp Pediatr. 2021;64(4):157-164. Published online February 4, 2021

Web of Science 12 Crossref 10

• Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) was detected in approximately 3% of neonates of mothers with coronavirus disease 2019 (COVID-19).
• Neonatal COVID-19 is relatively benign with 16%–22.4% cases asymptomatic.
• Neonates with pre-existing medical conditions and preterm infants are at a higher risk of severe COVID-19.
• Requirement for neonatal mechanical ventilation is 20%–22.4% (vs. 4% in children)
• Low birth weight (13.9%) and premature birth (22.2%) affect neonates of mothers with COVID-19.

DOI: https://doi.org/10.3345/cep.2020.01795

Infection

Epidemiology and clinical features of coronavirus disease 2019 in children

Soo-Han Choi, Han Wool Kim, Ji-Man Kang, Dong Hyun Kim, Eun Young Cho

Clin Exp Pediatr. 2020;63(4):125-132. Published online April 6, 2020

Web of Science 132 Crossref 135

Coronavirus disease-2019 (COVID-19), which started in Wuhan, China, in December 2019 and declared a worldwide pandemic on March 11, 2020, is a novel infectious disease that causes respiratory illness and death. Pediatric COVID-19 accounts for a small percentage of patients and is often milder than that in adults; however, it can progress to severe disease in some cases. Even neonates...

DOI: https://doi.org/10.3345/cep.2020.00535

Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19)

Su Eun Park

Clin Exp Pediatr. 2020;63(4):119-124. Published online April 2, 2020

Web of Science 314 Crossref 333

A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. The current outbreak of infections with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). COVID-19...

DOI: https://doi.org/10.3345/cep.2020.00493

Original Article

Association between Kawasaki disease and acute respiratory viral infections

Eun Young Cho, Byung Wook Eun, Nam Hee Kim, Jina Lee, Eun Hwa Choi, Hoan Jong Lee, Jung Yun Choi

Clin Exp Pediatr. 2009;52(11):1241-1248. Published online November 15, 2009

Purpose : The etiology of Kawasaki disease (KD) is still unknown. Recently, an association between human coronavirus NL63 (HCoV-NL63) and KD was implicated. Hence, we attempted to determine the association between KD and acute respiratory viral infections. Methods : Nasopharyngeal aspirate samples were obtained from 54 patients diagnosed with KD at the Seoul National University (SNU) Children’s Hospital and SNU-Bundang Hospital...

PDF

Cited By 25	Neurodevelopmental outcomes of preterm infants
Cited By 20	Association of gut microbiota with obesity in children and adolescents
Cited By 20	Long COVID in children and adolescents: prevalence, clinical manifestations, and management strategies
Cited By 19	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis
Cited By 18	Nonalcoholic fatty liver disease and insulin resistance in children

Search