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Volume 52(12); Dec 2009
Review Articles
Obesity in children and adolescents
Jeong Wan Seo
Korean J Pediatr. 2009;52(12):1311-1320.   Published online December 15, 2009
Childhood obesity has rapidly increased in Korea during the past 20–30 years. Approximately 1 of 10 children and adolescents is obese. Appropriate prevention and intervention measures urgently need. Obesity prevention starts early in life, i.e., obesity prevention and education begins during the period of fetal development in utero. Behavioral changes are the most positively reflected during pregnancy. Infants should be...
Prevention strategies for obesity in children and adolescents
Kyung Rye Moon
Korean J Pediatr. 2009;52(12):1321-1326.   Published online December 15, 2009
Prevalence of obesity in Korean children and adolescents has dramatically increased since the last 10–20 years. It is important to initiate prevention efforts early in childhood because prevalence of obesity in adolescence is the strongest predictor of its prevalence in adulthood. Intrauterine life, infancy, and preschool years may comprise the critical periods that are essential for the long-term regulation of...
Nutrition requirements in child and adolescent athletes
Jae Ock Park
Korean J Pediatr. 2009;52(12):1327-1336.   Published online December 15, 2009
Increasing numbers of children and adolescents prefer undertaking physical exercise to overcome overweight or obesity. Children and adolescents are in the growth stage and require adequate nutrient supply. More calories and nutrients are required especially when they are engaged in physical exercise. Exercise is the only means to increase lean body mass and decrease body fat, but adequate nutrient supply...
Original Articles
Taurine exerts neuroprotective effects via anti-apoptosis in hypoxic-ischemic brain injury in neonatal rats
Ji Eun Jeong, Tae Yeol Kim, Hye Jin Park, Kye Hyang Lee, Kyung Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Eok Su Seo, Woo Taek Kim
Korean J Pediatr. 2009;52(12):1337-1347.   Published online December 15, 2009
Purpose : Taurine (2-aminoethanesulfonic acid) is a simple sulfur-containing amino acid. It is abundantly present in tissues such as brain, retina, heart, and skeletal muscles. Current studies have demonstrated the neuroprotective effects of taurine, but limited data are available for such effects during neonatal period. The aim of this study was to determine whether taurine could reduce hypoxic-ischemic (HI) cerebral...
Changes in the expression of cytokines and apoptosis-related genes in children with infectious mononucleosis
Dae Sun Jo, Ji Hye Han, Sun Young Kim, Min Sun Kim, Ho Keun Yi, Dae-Yeol Lee, Pyoung Han Hwang
Korean J Pediatr. 2009;52(12):1348-1357.   Published online December 15, 2009
Purpose : The aims of this study were to identify the clinical characteristics and determine the changes in the expression of cytokines and apoptosis-related genes in children with infectious mononucleosis. Methods : Serological examinations of 15 pediatric patients diagnosed with infectious mononucleosis were performed prospectively. Peripheral blood from the patients was used to compare the composition of T cell subsets,...
Detection of nasopharyngeal carriages in children by multiplex reverse transcriptase-polymerase chain reaction
Ji Hye Shin, Hye Young Han, Sun Young Kim
Korean J Pediatr. 2009;52(12):1358-1363.   Published online December 15, 2009
Purpose : The aim of this study was to determine the prevalence of asymptomatic nasopharyngeal carriages in children using a multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) assay kit. Methods : We obtained nasopharyngeal swabs from 33 children without any underlying disease from July 25 to July 28, 2008. The children were free from the signs of respiratory tract infections at the...
The changes in signal-averaged electrocardiogram after surgical correction of congenital heart disease
Yeo Hyang Kim, Hee Jung Choi, Gun Jik Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
Korean J Pediatr. 2009;52(12):1364-1369.   Published online December 15, 2009
Purpose : To analyze abnormal ventricular activation in childhood congenital heart disease induced by postoperative changes in ventricular volume and pressure and ventricular scar formation using signal-averaged electrocardiography (SAECG). Methods : Fifty-two patients who had undergone open heart surgery (OHS) were enrolled. Patients were divided into the following 3 groups: right ventricular volume overload (atrial septal defect, group1), left ventricular...
Effect of GnRH analogue on the bone mineral density of precocious or early pubertal girls
Jeong Sook Lim, Heon-Seok Han
Korean J Pediatr. 2009;52(12):1370-1376.   Published online December 15, 2009
Purpose : Treatment of precocity with gonadotropin releasing hormone analogue (GnRHa) might theoretically exert a detrimental effect on the bone mass during pubertal development. We investigated the short-term changes in bone mineral density (BMD) during GnRHa treatment and the enhancement in the changes with the co-administration of GnRHa and human growth hormone (hGH). Methods : Forty girls with precocious or...
Analysis of gonadotropin-releasing hormone (GnRH) test results in girls with precocious puberty
Jung Yun Choi, Hyun-Ju Kang, Won Kyoung Cho, Kyoung Soon Kim, So Hyun Park, Seung Hoon Hahn, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee
Korean J Pediatr. 2009;52(12):1377-1382.   Published online December 15, 2009
Purpose : The gonadotropin-releasing hormone (GnRH) test results of girls with precocious puberty were analyzed to determine whether this test can efficiently and clearly differentiate between central precocious puberty (CPP) and other disorders. Methods : Clinical and laboratory data of 54 girls with precocious pubertal signs were reviewed. Intravenous GnRH test was performed with blood samples obtained at 0, 30,...
Case Reports
A case of glycogen storage disease type Ib
Moon-Sun Kim, Jae-Bok Park, Chang-Seok Ki, Jin-Kyung Kim
Korean J Pediatr. 2009;52(12):1383-1387.   Published online December 15, 2009
We report a case of an 18-month-old girl with glycogen storage disease type Ib (GSD Ib). Her neutrophil counts had gradually decreased to less than 500/µL by the age of 3 years. However, there were no recurrent bacterial infections. Mutation analysis of the glucose-6-phosphate translocase (G6PT) gene revealed a compound heterozygous missense mutation (Ala148Val/Gly273Asp).
The first Korean case of poland-Möbius syndrome associated with dextrocardia
Jiyoung Jung, Han Gyu Kim, Hae-Mi Ahn, Su Jin Cho, Eun Ae Park
Korean J Pediatr. 2009;52(12):1388-1391.   Published online December 15, 2009
Poland syndrome is characterized by unilateral absence or hypoplasia of the pectoralis muscle and variable degree of ipsilateral hand anomalies. Möbius syndrome is a congenital neurological disorder characterized by complete or partial facial paralysis. Although the pathogeneses of these diseases are not well-characterized, diminished blood flow to the affected side is thought to play a role. A male infant weighing...
A case of pulmonary vascular air embolism in a very-low-birth-weight infant with massive hydrops
Myo Jing Kim, Hee Joon Yu, Cha Gon Lee, Soo Kyoung Park, Yun Sil Chang, Won Soon Park
Korean J Pediatr. 2009;52(12):1392-1395.   Published online December 15, 2009
Pulmonary vascular air embolism is a rare and, universally, almost a fatal complication of positive pressure ventilation in newborn infants. Here, we report a case of this unusual complication in a very-low-birth-weight infant who showed the clinical and radiological features of this complication along with pulmonary hypoplasia and massive hydrops. The possible pathogenesis has been discussed and a brief review...