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Volume 35(5); May 1992
Medical Lecture Course
Pulsatile Growth Hormone Secretion
Sei Won Yang
J Korean Pediatr Soc. 1992;35(5):587-594.   Published online May 15, 1992
Original Articles
Quantification of Human Urinary Growth Hormone and Its Clinical Significance in the Diagnosis of Growth Hormone Deficiency
Seung Ryul Lee, Ho Seong Kim, Duk Hi Kim, Chang Mi Kim
J Korean Pediatr Soc. 1992;35(5):595-601.   Published online May 15, 1992
Twelve-hour nocturnal urine was collecte in 5 patients diagnosed of having complete GH deficiency, 6 of having partial GH deficiency and 7 persons as normal control group. The GH levels in urine collections were evaluated, and the results are as follows. 1) The GH level of normal control group was 16.76¡¾1.91ng/12hr, 59.00¡¾6.92ng/gCr, 16.24¡¾2.52ng/m2, 0.58¡¾0.12ng/kg. 2) The GH level of complete GH deficiency...
Color Doppler Echocardiographic Evaluation of Residual Ductal Flow After Surgical Ligation
I Seok Kang, Hyun Kwack, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
J Korean Pediatr Soc. 1992;35(5):602-606.   Published online May 15, 1992
We evaluated the incidence of residual ductal flow with color Doppler echocardiography and associated clinical findings in 63 patients who had undergone surgical ligation for isolated PDA, The interval between surgery and color Doppler echocardiographic evaluation ranged from 2 days to6.6 years(mean 7 months). In 40 patients, color Doppler echocardiographic studies were done within 1month after surgery. In 8 of...
Clinical Evaluation of Reactive Thrombocytosis in Childhood
Yoon Suck Suh, Young Yoo, Kwang Chul Lee, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1992;35(5):607-613.   Published online May 15, 1992
The platelet coiunt has not been part of routine hematologic profiles until recently, when the newer electronic blood cell counters began to include platelet count with all other blood cell counts. With the widespread use of newer generation electronic blood cell counters, elevated platelets coiunts are being encountered more ofter in pediatric practice. We reviewed all cases of marked thrombocytosis to...
Hepaplastin Test for Screen of Vitamin K Deficiency in Term and Preterm Neonates
Eun Mi Kim, Gyung Og Yu, Dong Rak Choi, Chong Young Park, Hae Ran Lee, Choon Myung Ro
J Korean Pediatr Soc. 1992;35(5):614-620.   Published online May 15, 1992
To screen vitamin K deficiency in term and preterm neonates, the authors conducted Hepaplastin test based on 40 term and 40 preterm neonates who were delivered at Han Gang Sacred Heart Hospital. Also we compared Hepaplastin activity of term neonates with that of preterm neonates. 0.5mg or 1mg of vitamin K1 was injected intramuscularly immediately after birth according to the...
Statistical Study of Accidental Pediatric Patients in Emergency Room
Hyo Jeong Kim, Kwang Ik Song, Jin Bok Hwang, Chang Ho Han, Hye Li Chung, Young Dae Kwon
J Korean Pediatr Soc. 1992;35(5):621-629.   Published online May 15, 1992
This study was designed to evaluate the prevalence and significant features of 3,234 pediatric accidental patients who visited emergency room during 6 years period from January 1982 to December 1987. 1) The accidental pediatric patients were 26.7% of total pediatric patients who visited emergency room The frequency of Childhood accidents was increased in later 2 years period(34.7%) compared with the early...
Clinical Study on 44 Cases of Infant Born to Polyhydramniotic Mother
Byung Min Moon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim
J Korean Pediatr Soc. 1992;35(5):630-638.   Published online May 15, 1992
Forty four cases of Polyhydramnios were studied clinically among 13,337 newborn infants delivered in Kwangiu Christian Hospital during the period from April 1, 1986 through March 31, 1990. 1) The incidence of polyhydramnios was 0.33%. 2) The mean gestational age was 37.2 week, and 18 cases(40.8%)were premature, while 3 babies (6.8%) were born postmaturely. 3) The mean birth weight was 2.3kg, with 30...
Clinical Significance of Rheumatoid Factor in Juvenile Rheumatoid Arthritis
Ki Joong Kim, Bo Young Yun, Joong Gon Kim
J Korean Pediatr Soc. 1992;35(5):639-645.   Published online May 15, 1992
Rheumatoid factor is a commonly used laboratory test by clinicians to assess the children with possible juvenile rheumatoid arthritis. To assess its diagnositc value and clinical significance we reviewed the case histories of the patients in whom latex agglutinating rheumatoid factor was tested during November 1988 to April 1991 at Seoul National University Children's Hospital. There were 61 patients with...
Inciedence of Sepsis Associated with Total Parenteral Nutrition Solutions Made in the Nursery and Pharmacy
Moon Chan Kim, Jin Won Park, Yun Joo Chung
J Korean Pediatr Soc. 1992;35(5):646-651.   Published online May 15, 1992
From 1985 to 1987, when Total Parenteral Nutrition (TPN) solutions was made in the nursery without laminar flow hood and other usual aseptic techniques (method 1), there was sepsis in 27% out of 33. From 1988 to 1990, to prevent high incidence of sepsis, TPN was made in the pharmacy under laminar flow hood and by pharmacist who wore scrub...
A Clinical Study on Duchenne Muscular Dystrophy
Moon Sun Yang, Su Ahn Chae, Ki Joong Kim, Yong Seung Hwang
J Korean Pediatr Soc. 1992;35(5):652-658.   Published online May 15, 1992
Twenty-five cases of Duchenne muscular dystrophy(DMD) who were diagnosed in the department of pediatrics, Seoul national university hospital (from Jan. 1985 to June 1991) were reviewed. The results were as follows. 1) All of the patients were male. 2) The onset of symptoms was between two and eight years of age. The peak incidence was at four years of age. 3) Chief complaints...
MIC and MBC of Oral Antimicrobial Agents Against Staphylococcus aureus
Min Hang Kim, Jin Won Park, Yun Joo Chung, Kyung Sik Ryoo, Myung Woong Chang
J Korean Pediatr Soc. 1992;35(5):659-666.   Published online May 15, 1992
Antimicrobial susceptibility for 25 stranis of methicillin senitive Staphylococcus (MSSA) and 25 strains of methicillin resistant Staphylococcus aureus (MRSA), isolated from in-patients at Kosin Medical Center from January, 1989 to July, 1990, were tested by the tube dilution method. 1) For MSSA, sensitivity tests showed 21% was sensitive to cefadroxil. Seventy one percent was intermediate and 8% was resistant. 2) 96% of...
Case Reports
A Case of Cloacal Deformity
Young Mi Jee, Seung Jin Lee, In Kyung Sung, Byung Churl Lee
J Korean Pediatr Soc. 1992;35(5):667-670.   Published online May 15, 1992
We experienced a case of cloacal deformity. This one day-old female neonate had hydrometrocolpos with vaginal atresia, imperforated anus, cloaca associated with hemivertebrae, left renal agenesis and right hydronephrosis. A brief review of related literature was made.
Acute Disseminated Encephalomyelitis
So Young Kim, Jong Woo Bae, Byung Churl Lee
J Korean Pediatr Soc. 1992;35(5):671-677.   Published online May 15, 1992
Acute disseminated encephalomyelitis is an uncommon immune mediated inflammatory disorder of the central nervous system. It may be defined as a monophasic encephalitis or myelitis of abrupt onset characterized by symptoms and signs indicative of damage chiefly of the white matter of the brain or spinal cord. The process may be severe and even fatal or mild and evanescent. The...
A Case of Prader Willi Syndrome
K.N. Kim, Y.T. Jang, S.Y. Choi, W.S. Kim
J Korean Pediatr Soc. 1992;35(5):678-683.   Published online May 15, 1992
Prader willi syndrome is characterized by infantile hypotonia, mental retardation, hyperphagia with obesity, and hypogonadism. The etiology of Prader Willi syndrome is still unknown; however, a hypothalamic defect has been postulated and recently, the deletion of long arm of chromosome 15 has been postulated and recently, the deletion of long arm of chromosome 15 has been considered as a cause...
Two Cases of Cornelia de Lange Syndrome
Yoon Jong Yoo, Ki Chan Na, Ho Seong Yoo, Sang Kee Park, Yong Bong Park
J Korean Pediatr Soc. 1992;35(5):684-690.   Published online May 15, 1992
The Cornelia de Lange syndrome is characterized by severe growth and mental retardation, typical face, and low-pitched growling cry. We had experienced two cases of Cornelia de Lange syndrome in korean male infants. The baby showed microbrachycephaly, typical appearance of face with low forehead, bushy eyebrows, long curely eyelashs, thin lip with cleft palate, low set ears, generalized hirsutism and growth retardation...
One Case of Ruptured Aneurysm of Vein of Galen
Nam Soo Park, Moo Young Song, Un Jun Hyoung, Jin Oh Lee, Eun Ryoung Kim
J Korean Pediatr Soc. 1992;35(5):691-695.   Published online May 15, 1992
The vein of Galen malformation is rare midline intracranial arteriovenous malformation that have been diagnosed more often at necropsy than in life. The majority of these malformations were seen in neonate, infancy and childhood, and the clinical symptoms and prognosis were depended on age of presentation. The authors report a case of ruptured Vein of Galen aneurysmal malformation. A...
Neonatal Purpura Fulminans due to Homozygous Protein C Deficiency
Jae-Hong Park, Sung-Sub Sim, Soo-Young Kim, Hee-Joo Jeon, Chan-Yung Kim, Hong Keun Oh, Jin-Yeong Jeong
J Korean Pediatr Soc. 1992;35(5):696-703.   Published online May 15, 1992
Homozygous protein C deficiency is a rare herediatary disorder of blood coagulation resulting in microvascular and venous thromboses, usually purpura fulminans, starting shortly after birth. Protein C serves to inactivate the active forms of factor V and VIII, and increase the rate of fibrin degradation. For confirmation of homozygous protein C deficiency, the infant should have undetectable protein...
A Case of Chronic Granulomatous Disease
So Young Lee, Dae Chul Kim, Sung Hee Oh, Hahng Lee, Hyang Eun Sohn, Wha Soon Chung, Young Hyeh Ko, Moon Hyang Park
J Korean Pediatr Soc. 1992;35(5):704-712.   Published online May 15, 1992
Chronic granulomatous disease (CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. Dissemination of ingested live organisms results in multiple granuloma in reticuloendothelial system and multiple abscesses manifested by recurrent pus-draining suppurative lymphadenopathy, subcutanous abscess, or impetiginous skin rahses, pheumonitis, and hepatosplenomegaly, ultimately resulting in death. Two...
A Case of D13 Ring Chromosome Syndrome
Sung Lae Park, Ho Jun Im, Jae Hun Shin, Hahng Lee, Myung Soo Lyu, Yong Kyun Paik
J Korean Pediatr Soc. 1992;35(5):713-717.   Published online May 15, 1992
A case of D13 Ring Chromosome Syndrome, confirmed by chromosome study, was described. She was 8 years and 4 months old, and menifested facial abnormalities, psychomotor retardation and other multiple congenital abnormalities.
A Case of 8q2 Trisomy
Kwang Ik Song, Hyo Jeoing Kim, Jin Bok Hwang, Chang Ho Han, Hye Li Chung, Young Dae Kwon
J Korean Pediatr Soc. 1992;35(5):718-722.   Published online May 15, 1992
A case of 8q2 trisomy with mental retardation and mutiple congenital anomalies has been presented with the review of related literatures. The patient was 6 month old male child with mild mental and growth retardation, microcephaly, flat occiput, hypertelorism, broad and flat nose, low-set and promient cupped ears, micrognathia, short and wide neck, widely spaced nipples, thoracolumbar scoliosis, single transverse...
A Case of Congenital Giant Pigmented Nevus
Seung Wan Lee, Wu Ha You, Chang Bin Im, Chang Woo Lee, Chan Kum Park
J Korean Pediatr Soc. 1992;35(5):723-728.   Published online May 15, 1992
The congenital giant pigmented nevus, also known as bathing trunk nevus, is a severely disfiguring lesion covering large areas of the body surface. Although the occurrence of giant nevi in childhood is uncommon, it is frequent enough to represent a source of guilt for parents, and psychic trauma, and is advised. For those patients who do not choose to undergo...