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Volume 45(5); May 2002
Clinical Lecture
Hepatitis in Children
Jae Sung Ko
J Korean Pediatr Soc. 2002;45(5):553-559.   Published online May 15, 2002
Erratums
Cellular and Biochemical Mechanism of Perinatal Hypoxic-Ischemic Brain Injury
Young Pyo Chang
J Korean Pediatr Soc. 2002;45(5):560-567.   Published online May 15, 2002
Mouse Model of Bronchial Asthma
Yeong-Ho Rha
J Korean Pediatr Soc. 2002;45(5):568-574.   Published online May 15, 2002
Original Articles
A Survey on the Understanding of Breast-feeding in Pregnant Woman
Jeong Wan Seo, Yong Joo Kim, Kee Hyoung Lee, Jae Young Kim, Jay G Sim, Hae Soon Kim, Jae Sung Ko, Sun Hwan Bae, Hye Sook Park, Beom Soo Park
J Korean Pediatr Soc. 2002;45(5):575-587.   Published online May 15, 2002
Purpose : To investigate the understanding of breast-feeding in pregnant woman and the proper way of encouraging breast-feeding. Methods : Each questionnaire included items about demographic characteristics and the understanding of breast-feeding. The questionnaires were filled up by pregnant women visiting obstetric clinics in Seoul and its vicinities, Busan, Choongjoo and Chungjoo from July 2001 to August 2001. One thousand, two...
Effects of Obesity on Pulmonary Functions in Children
Seok Won Park, Hwang Min Kim, Jong Soo Kim, Jae Kuk Cha, Hae Ran Lee
J Korean Pediatr Soc. 2002;45(5):588-595.   Published online May 15, 2002
Purpose : The incidence of obesity has increased in Korea recently. Obesity leads to higher risks of hypertension, hyperlipidemia and insulin resistance. It also leads to risks of respiratory complications. This study was performed to see the effects of obesity on children's pulmonary functions and on developed bronchospasm after exercise loading according to their obesity degrees. Methods : 257 obese...
Peripheral Neutrophil Count and Respiratory Failure in Preterm Infant
Kum Joo Lee, Soo Young Yun, Ran Lee, Jae Ho Hean, Ghee Young Jung, Jin Hee Park, Young Sun Park
J Korean Pediatr Soc. 2002;45(5):596-602.   Published online May 15, 2002
Purpose : The purpose of this study was to analyze the association of peripheral neutrophil count with the development of respiratory failure in preterm infants. Methods : A retrospective study was conducted from January 1993 to December 1999 on 44 preterm infants, who were admitted to the neonatal intensive care unit of St. Francisco hospital. Preterm infants(birth weight 500 to 1,350...
Epidemiologic and Clinical Features of Pertussis in Children(2000. 3-2001. 3)
Shin Yoo, Kyong Ouk Ahn, Eun Hye Park, Hyun Sang Cho, Chong Young Park, Hae Ran Lee
J Korean Pediatr Soc. 2002;45(5):603-608.   Published online May 15, 2002
Purpose : Pertussis is a highly communicable infectious disease in children with high mortality, especially in young infants. The incidence of pertussis in South Korea has decreased to about 10 cases a year in late '90s. Doubting previously reported incidences of pertussis, we designed this study to establish exact epidemiology and a diagnostic basis of pertussis. Methods : From Mar. 2000...
Natural Course of Atrial Septal Defect Diagnosed Within the First 4 Weeks of Life
Young Jun Hwang, Kyung Hyun Chung, Suk Min Choi, Kyu Hyung Lee
J Korean Pediatr Soc. 2002;45(5):609-614.   Published online May 15, 2002
Purpose : The purpose of our investigation was to explore the natural course, and the factors that influence the natural course, in ostium secundum atrial septal defect(ASD) diagnosed within the first 4 weeks of life. Methods : We studied patients with ASD diagnosed within the first 4 weeks of life during the period from September 1995 to September 1999 in our...
Study of Neonatal Cardiac Catheterization for Over the Last 10 Years
Jinyoung Song, Sungkyu Lee, Jaeyoung Lee, Sujin Kim, Wooseup Shim
J Korean Pediatr Soc. 2002;45(5):615-621.   Published online May 15, 2002
Purpose : The neonatal cardiac catheterization and angiogram for transcatheter therapy are still essential methods in congenital heart disease, so we reviewed our experience with neonatal cardiac catheterization over 10 years at a single institution. Methods : A retrospective review of all 139 neonatal catheterizations from January 1991 to December 2000 at Sejong Heart Institution was performed. The purpose of the...
Clinical Manifestation and Associated Cardiac Anomalies of Dextrocardia
Sung Hoon Kim, Seung A Hong, Yoon Jung Cho, Sang Lak Lee, Tae Chan Kwon
J Korean Pediatr Soc. 2002;45(5):622-628.   Published online May 15, 2002
Purpose : The purpose of this study is to ascertain the clinical manifestations and associated cardiac anomalies of dextrocardia. Methods : Twenty-four pediatric patients, who were admitted to, or visited, Dongsan Medical Center Keimyung University and were diagnosed with dextrocardia between January 1996 and July 2001, were enrolled in this study. All patients received echocardiogram and abdominal ultrasonogram to identify...
Characteristics of Seizures and Neuronal Nitric Oxide Synthase Expression of Hippocampus in Hyperthermia-Induced Seizures of Developing Rat
Doo-Kwun Kim, Dong-Keun Jung
J Korean Pediatr Soc. 2002;45(5):629-636.   Published online May 15, 2002
Purpose : Our study was aimed to investigate the characteristics of seizures as well as to determine whether the expression of neuronal nitric oxide synthase expression(nNOS) of hippocampus has an affect in the hyperthermic seizure in developing rat. Methods : Hyperthermic seizures were repeatedly induced twice a week for four weeks in 20-day old Spraque-Dowley rats. Fifty two rats were used...
A Study of Receptor Expression in Leukocytes by Quantitative Fluorescence Measurement
Kyung Hyo Kim, Ju Young Seoh
J Korean Pediatr Soc. 2002;45(5):637-645.   Published online May 15, 2002
Purpose : It is well known that the receptors for Fcγ moiety of IgG(FcγR) are instrumental in antibody-mediated clearance of microorganisms by granulocytes and monocytes, and immune regulation in lymphocytes. Furthermore, complement receptor-3(CR3) is also important in neutrophilic adhesion, diapedesis, and phagocytic functions. In an attempt to examine their roles in neonates, we compared the expressions of FcγRs and CR3...
Type 2 Diabetes Mellitus in Children
Jee Min Park, Eun Gyong Yoo, Duk Hee Kim
J Korean Pediatr Soc. 2002;45(5):646-653.   Published online May 15, 2002
Purpose : The incidence of type 2 diabetes mellitus in children has been increasing worldwide recently, which is thought to be related to the increasing prevalence of obesity. We investigated to evaluate the incidence and the characteristics of type 2 diabetes mellitus in children and also analysed the relationship between intrauterine growth retardation and type 2 diabetes mellitus. Methods :...
A Change of Adrenal Androgen and Cortisol in Kawasaki Disease
Sun-Hee Lee, Jae-Hong Yu, Hong-Ryang Kil
J Korean Pediatr Soc. 2002;45(5):654-658.   Published online May 15, 2002
Purpose : Endocrine and immune systems are connected and interdependent. Adrenal glands play an important role in this network and control the balance between serum levels of dehydroepiandrosterone sulfate(DHEAS) and cortisol. These steroids have an antagonistic effect on the T cell progression into Th1 and Th2 cells and on the induction of correlated interleukins. Therefore we evaluated the role of...
Case Reports
A Case of Dominantly Inherited β Thalassemia Due to Hb Dieppe
You Kyoung Choi, Hong Jin Lee, Won Il Park, Kyung Ja Lee, Sung Ha Kang, Ji Yeon Kim, Sung Sup Park
J Korean Pediatr Soc. 2002;45(5):659-663.   Published online May 15, 2002
β thalassemias are usually transmitted as autosomal recessive traits. However, some dominant forms of β thalassemia have been identified in individuals who have inherited a single copy of an abnormal β globin gene. Thalassemia intermedia with mild anemia, jaundice, and splenomegaly has been observed in these patients. Electrophoresis has shown elevated Hemoglobin(Hb) A2 and Hb F levels. In particular, there...
Hemophagocytic Syndrome with Kawasaki Disease and Peripheral Gangrene
Hwa Jun Yun, Ko Woon Jeon, Hwang Min Kim, Seok Won Park, Young Uh
J Korean Pediatr Soc. 2002;45(5):664-668.   Published online May 15, 2002
A twenty six months-old boy developed hemophagocytic syndrome during the course of Kawasaki disease. Despite the appropriate treatment modalities for Kawasaki disease, he developed thrombocytopenia, hepatomegaly, high-grade fever, hypertriglyceridemia, peripheral gangrene, and evidence of hemophagocytosis in bone marrow biopsy. Although the course was stormy, he responded well to a combination therapy of corticosteroid and etoposide.
A Case of Respiratory Difficulty Due to Congenital Tracheal Calcification and Nasal Pyriform Aperture Stenosis
Kyu Tae Kim, Young Mi Kim, Su Eun Park, Jae Hong Park, Hawn Jung Noh, Hak Jin Kim
J Korean Pediatr Soc. 2002;45(5):669-672.   Published online May 15, 2002
Nasal obstruction is a cause of respiratory distress in newborns. The congenital nasal airway obstructive abnormalities are classified into three forms according to the location: posterior choanal atresia, nasal cavity stenosis and congenital nasal pyriform aperture stenosis(CNPAS). CNPAS is located at the anterior part of the nasal fossa. CT is the study of choice to make the diagnosis of CNPAS...
A Case of Cerebral Infarction Complicated by Mycoplasma pneumoniae Pneumonia
Kyoung Whoon Cheon, Won Sik Kang, Byeong Hee Son, Sung Won Kim
J Korean Pediatr Soc. 2002;45(5):673-678.   Published online May 15, 2002
Mycoplasma pneumoniae is the most common pathogen of the respiratory tract among school- aged children and young adults. The incidence of CNS complication is reported as 0.1-7% of Mycoplasma pneumoniae infections. We experienced a case of cerebral infarction complicated by Mycoplasma pneumoniae, and reviewed the literature about the CNS complication of Mycoplasma pneumoniae infection.
A Case of 18q-Deletion Syndrome with Hydronephrosis and Anhydrosis
Mun Hee Kim, Kee Hwan Yoo, Young Sook Hong, Soon Kyum Kim
J Korean Pediatr Soc. 1999;45(5):711-715.   Published online May 15, 1999
The 18q-syndrome is a deletion disorder that occurs in humans. Clinical symptoms are mental retardation, craniofacial anomalies, skeletal deformity, seizure, and hearing loss. 18q- deletion occurs over a broad region, spanning the interval from 18q22.2 to 18qter rather than a single critical region containing 18q. We experienced a case of 18q-syndrome in a male child. It was diagnosed by clinical...