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Volume 39(7); Jul 1996
Medical Lecture Courses
Diagnostic Imaging in Pediatric Central Nervous System
In-One Kim
J Korean Pediatr Soc. 1996;39(7):885-893.   Published online July 15, 1996
Molecular Genetics on the Hereditary Neurodegenerative Disorders caused by Trinucleotide Expansion
Dong Kyu Jin
J Korean Pediatr Soc. 1996;39(7):894-900.   Published online July 15, 1996
Clinical Lecture
Diagnosis and Treatment of Childhood Hemorrhagic Disorders
Hack Ki Kim
J Korean Pediatr Soc. 1996;39(7):901-907.   Published online July 15, 1996
Original Articles
The Change of Serum Cholesterol level in Children with Fever
Mi Ja Park, Jae Yoon Kim, Jae Wook Ko, Don Hee Ahn
J Korean Pediatr Soc. 1996;39(7):908-914.   Published online July 15, 1996
Purpose : This study was undertaken to assess the change of the serum cholesterol level according to the duration of fever in children. Methods : A retrospective study presents data on fasting serum cholesterol assessed 346 children aged from 3 to 14 years, admitted to National Medical Center from Jan. 1992 to Jun. 1994 due to febrile disease. These patients were divided into three...
Molecular Genetic Screening for the SRY(Sex Determining Region of the Y chromosme) Gene in Turner Syndrome Patients
Jung-Yeon Shim, Han-Wook Yoo
J Korean Pediatr Soc. 1996;39(7):915-923.   Published online July 15, 1996
Purpose : Turner syndrome is among the most common cytogenetic abnormalities associated with X chromosome. In only 40-60% of Turner syndrome, 45,X monosomy is found and the high prenatal mortality of non-mosaic 45,X has led to the hypothesis that liveborn 45,X individuals may be cryptic mosaics. The presence of Y chromosome is significant because it predisposes affected individuals with Turner syndrome to gonadoblastoma formation....
Significance of Creatine Kinase Isoenzymes for Neurologic Outcome in Perinatal Asphyxia
Mi Kyung Son, Eun Sik Kang, Sun Hi Jung, Kyuchul Choeh
J Korean Pediatr Soc. 1996;39(7):924-933.   Published online July 15, 1996
Purpose : To investigate the usefulness of the serum Creatine kinase(CK), especially brain typical creatine kinase(CK-BB) as an indicator of brain damage extent, mortality and long term nurologic sequelae, the study was done. Methods : CK and CK isoenzyme activites were measured at 6-10 hours after birth in 160 asphyxiated newborn infants who admitted in Eulji General Hospital from August 1990 to July 1994. Infants...
Varicella Zoster Virus Spicific IgG Antibody Titer in Vaccinated and Infected Children
Young Eun Lee, Eun Ae Park, Kyung hee Kim
J Korean Pediatr Soc. 1996;39(7):934-942.   Published online July 15, 1996
Purpose : Varicella is mild self limited disease with vesicular skin eruption but highly contagious and accompanied many complications. Especially, varicella is fatal in leukemic children and immunocompromised children. The live varicella zoster virus was first developed by Takahashi et al. in the 1974. This vaccine has now been licensed for general use in Europe and the United States as well as in Korea.. The...
Cold Agglutinin and Mycoplasma Antibody Titersin Children with Mycoplasma pneumoniae Pneumonia During Recent 5 Years
Seon Hwa Yoon, Joon Kyo Jung, Myung Ho Oh
J Korean Pediatr Soc. 1996;39(7):943-952.   Published online July 15, 1996
Purpose : More effective diagnosis and treatment through a survey on clinical aspect for the last 5 years and interrelation between cold agglutinin titer and mycoplasma antibody titer of Mycoplasma pneumoniae pneumonia. Methods : 369 patients hospitalized in the department of pediatrics of Chung Goo Sung Shim Hospital for the 5 years from January 1990 to December 1994 have been surveyed, which diagnosed to be...
Arterial Oxygen Desaturation after Salbutamol Nebulization in Wheezy Infants and Children
Eun Sun Yoo, Jung Won Seo, Seung Joo Lee
J Korean Pediatr Soc. 1996;39(7):953-961.   Published online July 15, 1996
Purpose : Nebulized selective β2-adrenoreceptor agonists have been widely used in acute asthma and selectively in acute bronchiolitis. However, nebulized salbutamol have been reported to cause arterial oxygen desaturation in some of the acute bronchiolitis and severe asthma patients. This may be the results of a paradoxical bronchoconstriction linked to acidic and hyper-osmolar nebulized salbutamol solution and etc. We assessed the changes in arterial...
Comparison of Left and Right Ventricular Volume and Cardiac Output by MRI and Echocardiography
Young Mi Hong
J Korean Pediatr Soc. 1996;39(7):962-969.   Published online July 15, 1996
Purpose : Ventricular volume and cardiac output are very important to evaluate cardiac fuction. Cine MRI has been found to a feasible technique in evaluating cardiac anatomy and cardiovascular function in a variety of cardiac disease. Measurement of left ventricular volume by cine MRI was closely correlated with the result by echocardiography or cine angiography. The purpose of this study is to compare the...
Correlation between Plasma Endothelin-1 Concentrations and Pulmonary Hypertension Associated with Congenital Heart Defects
Sang Ook Park, Su Eun Park, Hyang Jae Yoo, Young Tak Lim, Hee Ju Park
J Korean Pediatr Soc. 1996;39(7):970-976.   Published online July 15, 1996
Purpose : Endothelin-1 is the most potent vasoconstrictor. This study was investigated the correlation of plasma endothelin-1 and pulmonary hypertension associated with congenital heart defect. Methods : We evaluated the concentration of ET-1 in 24 cases of congenital heart disease diagnosed at the Department of Pediatrics, Pusan National University, from December 1993 to September 1994. The patients were divided into 2 groups according to mean...
Serial Changes of Doppler Echocardiographic Transvalvular Velocity during the Neonatal Period in Full Term Neonates
Woo Taek Kim, Myung Chul Hyun, Sang Bum Lee
J Korean Pediatr Soc. 1996;39(7):977-986.   Published online July 15, 1996
Purpose : We performed this study to compare serial measurements which relate to both ventricular functions in full term neonates for the first three weeks after birth. Methods : Echocardiographic and pulsed Doppler studies were performed for 20 newborns during the first 36 hours of life, and subsequent serial studies in the second (n=13) and third(n=12) weeks of life. Evaluation included measurements of both...
Primary Distal Renal Tubular Acidosis in Children
Byoung Chul Kang, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi
J Korean Pediatr Soc. 1996;39(7):987-996.   Published online July 15, 1996
Purpose : This study was designed to examine the clinical characteristics and the effect of treatment in children with primary distal renal tubular acidosis (dRTA). Methods : Medical records of 4 children diagnosed as dRTA at Seoul National University Children's Hospital were reviewed, and the clinical manifestations, laboratory findings, diagnostic criteria and effects of treatments were investigated. Results : All cases presented with growth retardation....
The Effect of Recombinant Human Growth Hormone on the Growth in the Children with Chronic Renal Failure
Sei Won Yang, Young Choi
J Korean Pediatr Soc. 1996;39(7):997-1004.   Published online July 15, 1996
Purpose : We observed the effect of three year-administration of recombinant human growth hormone(rhGH) on the growth in the children with chronic renal failure(CRF). Methods : Five prepubertal children(three boys and two girls) with CRF, who had been managed by conservative methods, were given rhGH(1 U/kg/week) for three years. Growth parameters, such as growth velocity, height standard deviation score(SDS), and predicted final adult height, obtained...
Case Reports
Herditary Anhidrotic Ectodermal Dysplasiain Twins
Myung Gil Han, Do Hyun Kim, Hyung Ro Moon
J Korean Pediatr Soc. 1996;39(7):1005-1009.   Published online July 15, 1996
Hereditary anhidrotic ectodermal Dysplasia is a congenital disease displaying characteristics of anhidrosis, hypotrichosis and dental defect which are caused by developmental anomaly of ectodermal epidermis and its appendages. We experienced two cases of hereditary anhidrotic ectodermal dysplasia in two-year and four-month old twin brothers. These patients suffered from intermittent high fever early in life which brought them to our clinical attention. However the diagnosis of...
A Case of Brainstem Encephalitis
Tae Hoon Kang, Ki Ook Kim, Gyu Geun Hywang
J Korean Pediatr Soc. 1996;39(7):1010-1014.   Published online July 15, 1996
We experienced a case of brainstem encephalitis that is possibly caused by herpes simplex virus infection in a 3 year-old girl. The diagnosis was made by clinical symptoms, neurologic exam, serologic test, brain CT, brain MRI and brainstem biopsy. Herpes simplex virus specific antibody was detected from cerebrospinal fluid and the titer was 11.78 by enzyme immunoassay. Stereotaxic brainstem biopsy was done for differenciate...
A Case of Pyloric Atresia Associated with Epidermolysis Bullosa
Mi Kyung Son, Te Kyung Lee, He Jin Choeh, Kyuchul Choeh
J Korean Pediatr Soc. 1996;39(7):1015-1019.   Published online July 15, 1996
We have experienced a case of congenital pyloric atresia associated with epidermolysis bullosa in a premature newborn who was born at the gestation period of 33+3 week. She showed a few blisters on left ankle at birth and the easy formation of blisters involving the area of trauma or friction with depigmentation after healing. The histologic finding of the lesion showed junctional epidermolysis bullosa. Abdominal...
A Case of Mauriac's syndrome
Se Young Kim, Choong Ho Shin, Il Soo Ha, Hae Il Cheong, Sei Won Yang, Yong Choi, Hyung Ro Moon
J Korean Pediatr Soc. 1996;39(7):1020-1024.   Published online July 15, 1996
Mauriac's syndrome was described in the 1920s, as a triad of poorly controlled insulin dependent diabetes mellitus, profound growth retardation, and hepatomgaly. Following the wide availability of insulin and intensification of diabetic control, this entity has become quite rare. A 9-year-old female child was transferred to pediatric OPD of SNUCH because of hyperglycemia, short stature, and visual disturbance. Five years prior to admission, she...
A Case of Inflammatory Linear Verrucous Epidermal Nevus
Hye Kyong Yoon, Dae Eui Hong, Sung Dong Choi, Seung Yun Jung, Byung Kyu Suh, Jin Han Kang, Sang Hyun Cho
J Korean Pediatr Soc. 1996;39(7):1025-1028.   Published online July 15, 1996
Inflammatory linear verrucous epidermal nevus(ILVEN) is a relatively rare skin disorder, characterized by chronic inflammatory psoriasiform pattern. This chronic skin disorder is generally believed to be resistant to various treatments, although some authors have reported success with 13-cis-retinoic acid and 585 nm pulsed laser therapy. We experienced a 15-month aged female ILVEN patient who has been suffered from linear erythematous verrucous pathes mainly located on...
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