Clinical and Experimental Pediatrics

Search

Page Path

HOME
Search

Original Article

Hematology

Changes and correlations of T-cell coinhibitory molecule programmed death-1 and interferon-γ in pediatric immune thrombocytopenia

Fady Mohamed El-Gendy, Amira M.F. Shehata, Esam Awad Abd El-Kawy, Mahmoud Ahmed El-Hawy

Clin Exp Pediatr. 2023;66(3):127-133. Published online February 24, 2023

Web of Science 2 Crossref 1

Question: What are the PD-1⁺ CD4⁺ T cells percentages and serum interferon gamma (IFN-γ) levels of pediatric patients with immune thrombocytopenia (ITP)?
Finding: Compared with healthy controls, the PD-1⁺ CD4⁺ T cells percentages and IFN-γ levels were significantly higher in ITP patients before and 1 month after therapy.
Meaning: Our findings suggest that PD-1⁺ CD4⁺ T cells and IFN-γ are involved in the pathophysiological process of ITP.

DOI: https://doi.org/10.3345/cep.2022.00920

MOST CITED ACCEPTED ARTICLES

Cited By 20	Neurodevelopmental outcomes of preterm infants
Cited By 19	Long COVID in children and adolescents: prevalence, clinical manifestations, and management strategies
Cited By 17	Association of gut microbiota with obesity in children and adolescents
Cited By 14	Gut microbiota affects brain development and behavior
Cited By 14	Nonalcoholic fatty liver disease and insulin resistance in children

+more

Association between macrophage migration inhibitory factor gene and growth differentiation factor 15 gene polymorphisms and circulating levels with respiratory distress syndrome among preterm neonates

Role of miRNA-146a and miRNA-125b in Helicobacter pylori

Clinical course of children with postinfectious bronchiolitis obliterans with versus without comorbid bronchopulmonary dysplasia

Myopia: a review of current concepts, association with nonophthalmological conditions, and treatment strategy in children and adolescents

Effect of vitamin C supplement in treatment of childhood pneumonia requiring hospitalization: A randomized controlled trial

+more

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES

FOR CONTRIBUTORS

ABOUT

Editorial Office: Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306 Fax: +82-2-3473-7307 E-mail: office@e-cep.org

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)