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Telomere biology disorders in childhood interstitial lung disease: new insights from the chILD-EU cohort

Andrew Courtwright

Clin Exp Pediatr. 2026;69(7):542-544. Published online June 30, 2026

Greiner-Mai et al. expand recognition of telomere biology disorder (TBD)-associated interstitial lung disease (ILD) in children, demonstrating heterogenous radiographic and ILD subtypes in combination with variable extrapulmonary phenotypes, even in the absence of ultrashort peripheral blood telomere length (TL). While their findings highlight some of the limitations of current TL testing methods, they introduce critical questions regarding family screening and the role of antifibrotic and telomere-directed therapies in children with TBD-related ILD.

DOI: https://doi.org/10.3345/cep.2026.01389

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