Clinical and Experimental Pediatrics

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Original Article

Serum Level of G-CSF and GM-CSF and CFU-GM Response to Hematopoietic Growth Factors in a Patient with Cyclic Neutropenia

Youn-Kyung Lee, Seok-Hun Kim, Kwang-Woo Kim, Soon Lee, Heung-Sik Kim, Dong-Seok Chun, Kun-Soo Lee

Clin Exp Pediatr. 2001;44(10):1168-1175. Published online October 15, 2001

Purpose : Serum levels of G-CSF and GM-CSF were measured and CFU-GM assay using G- CSF, GM-CSF and SCF was conducted to evaluate the influence of hematopoietic growth factor on the precursor cells of cyclic neutropenia. Methods : A 7-year-old male with cyclic neutropenia was studied. Marrow mononuclear cells were isolated at neutrophil nadir and recovery and cultured in methylcellulose media...

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