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Case Report
A Case of Toxic Epidermal Necrolysis in Early Infancy
Min Seong Kim, Jeong Nyun Kim, Bang Soon Kim, Hong Joo Kim, Myung Jae Chey, Churl Young Chung
Clin Exp Pediatr. 1999;42(11):1594-1598.   Published online November 15, 1999
Toxic epidermal necrolysis(TEN) is a bullous disorder affecting mainly basal layers of epidermis by hypersensitive reaction. It is rarely reported in infants under six months of age. It can be developed by drug, infection, and vaccination, which makes it difficult to differentiate from staphylococcal scalded skin syndrome(SSSS) especially in early infancy. We report a case of TEN in a 6-week-old...
Original Article
Clinical Trial of Domestically Developed Bovine Lung Surfactant YY-38 in Neonatal Respiratory Distress Syndrome
Chul Lee, Jeong Nyun Kim, Min-Soo Park, Moon Sung Park, Shin Won Yoon, Wook Chang, Ran Namgung, Kook In Park, Dong-Gwan Han
Clin Exp Pediatr. 1999;42(4):472-483.   Published online April 15, 1999
Purpose : We previously reported modified bovine lung surfactant YY-38(NewfactanⓇ) had a low surface tension, good hysteresis, and exhibited good pressure-volume curve in animal experiment (J Korean Pediatr Asso 1997;40:771-85). We performed multicenter clinical trial of NewfactanⓇ in neonatal RDS. Methods : Seventy-seven infants with RDS(GA 31.8¡¾2.9 wks and BW 1,809¡¾592 gm) in 4 NICU were enrolled. After administration of...
Comparison of Treatment Course and Outcome between Medically and Surgically Treated Patent Ductus
Jeong Geun Kim, Jeong Nyun Kim, Dong Chul Park, Shin Yeong Lee, Hyun Chul Lee, Myung Jae Chey, Churl Young Chung,
Clin Exp Pediatr. 1998;41(10):1334-1341.   Published online October 15, 1998
Purpose : Early intervention is needed to treat patent ductus arteriosus(PDA) as it is a major cause of increased mortality in preterm infants. However, it is uncertain which is better, medical versus surgical management. We reviewed medical records to compare the treatment course and outcome between medically and surgically treated preterm PDA infants. Methods : Thirth-two Mechanically ventilated pretem infants(gestational age<34...
Thyroid Hormone Concentrations in Preterm Infants
Sung Keun Moon, Jeong Nyun Kim, Mi Jung Park, Myung Jae Choi, Chrul Young Chung
Clin Exp Pediatr. 1998;41(10):1324-1328.   Published online October 15, 1998
Purpose : To establish reference ranges for thyroid hormone concentrations in premature infants, we measured T4 and thyroid stimulating hormone(TSH) concentrations and analyzed the relation to gestational age and birth weight. Methods : Serum T4 and TSH concentrations were measured by radioimmunoassay for 391 premature infants born in Sanggye Paik Hospital for two years and eight months. Results : Gestational age of...
Risk factors for Pulmonary Interstitial Emphysema(PIE) in Mechanically Ventilated Neonates with Hyaline Membrane Diseas
Shin Won Yoon, Chul Lee, Jeong Nyun Kim, Ran Namgung, Dong Gwan Han, Myung Joon Kim
Clin Exp Pediatr. 1997;40(3):318-326.   Published online March 15, 1997
Purpose : Pulmonary interstitial emphysema(PIE) is a common and serious complication of mechanical ventilation in infants with hyaline membrane disease. This abnormal collection of gases has two basic roentgenographic features; linear and cyst-like radiolucencies. High positive inspiratory pressure was found to be the most significant parameter associated with development of fatal pulmonary interstitial emphysema. Without prompt conservative management such as lowering peak inspiratory...
Clinical Observations of Transient Idiopathic Hypocalcemia
Jeong Nyun Kim, Mi Jung Park, Duk Hi Kim, Ho Sung Kim
Clin Exp Pediatr. 1995;38(9):1193-1200.   Published online September 15, 1995
Purpose : In concern of diagnosis and treatment of transient idiopathic hypocalcemia, a major cause of infantile, we studied the onset of age, clinical characteristics, laboratory findings, and duration of treatment and recovery of transient idiopathic hypocalcemia. Methods : The author observed 19 infants with transient idiopathic hypocalcemia who had been admitted to Yonsei university hospital due to convulsion for 4...