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Original Article

Studies on the diuretic activity of the serum of the patient with diabetes insipidus

Kook-Choo Rie, Yong-Soo Yun, Ho-Sung Lee, Jeong-Ki Seo, Dong-Hwan Lee

Clin Exp Pediatr. 1976;19(2):99-112. Published online February 28, 1976

Diabetes insipidus is the syndrome which results from abnomality in production or release of ADH. Recently there have been used two nonhormonal forms of therapy in the treatment of DI: 1)Various diuretics, primarily thiazides and 2)The oral hypoglycemic agents, the sulfonlureas. Arduino and other numerous invesgators demnstrated that sulfonylurea chlorpropamide (Diabinase) and tolbutamide(Drinase) had a ADH-Iike effect in a patient...

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