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Original Article

Effect of maternal thyroxine treatment on the offspring's brain development with fetal alcohol effects in the rats

Jin Fu, Yoon Young Chung, Sang Kee Park

Clin Exp Pediatr. 2006;49(6):677-685. Published online June 15, 2006

Purpose : This study aimed to investigate whether exogenous thyroxine(T4) treatment to alcohol-fed dams would ameliorate the detrimental effects of alcohol on the postnatal development of neuropeptide-Y(NPY)-containing neurons of the cerebral cortex and hippocampus of the offspring. Methods : Time-pregnant rats were divided into three groups. An alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day...

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