Clinical and Experimental Pediatrics

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Original Article

Inhibitory effects of several drugs to intestinal secretory stimulation of heat-labile enterotoxin produced by enterotoxigenic E. coli.

Kyung Rae Moon, Sang Kee Park, Young Wook Chun, Kap Seung Kim, Young Bong Park, Young Cheon Na, Jeong Hyung Park, Hyun Kook Lee, Nam Ung Yang

Clin Exp Pediatr. 1991;34(9):1231-1239. Published online September 30, 1991

For exploitation of new antidiarrheal agents to heat-labile enterotoxin (LT) produced by enterotox- igenic E. coli, we have tested several drugs by rabbit ileal loop assay and obtained some significant results. L-glutathione (20 mg), P-chloromercuriphenyl sulfonic acid (20 mg) and water heating extract of Prunus mume (20 mg) reduced LT-mediated intestinal fluid secretion in rabbit ileal loop assay by 92%, 87%, 92% respectively. Maleate,...

Seroconversion rate of measles specific IgG antibody in previously vaccinated children.

Kyeoing Hun Cha, Eun Kyeong Jung, Kyung Rae Moon, Kap Seung Kim, Sang Kee Park, Yeong Bong Park

Clin Exp Pediatr. 1991;34(8):1080-1085. Published online August 31, 1991

This study was performed to evaluate the changes of measles specific IgG antibody titer using enzyme linked immunosorbent assay (ELISA) on the sera of various groups of age. We obtained the following result: 1) Out of 118cases, 99cases (83.9%) were vaccinated children and 19cases (16.1%) were unvac- cinated children. Among them, the number of cases who had been infected with measles were 17 cases (17.2%) in...

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