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Case Report

A Case of Pure Red Cell Anemia Complicated by Antiepileptic Drugs

Hyunmi Kim, Sang Gyu Park, Sung Ryeul Kim

Clin Exp Pediatr. 1999;42(2):264-267. Published online February 15, 1999

A 12-year-old boy developed pure red cell anemia(PRCA) during a combination therapy of antiepileptic drugs(AEDs) for epilepsy. His complex partial seizure was intractable to monotherapy. During 7 months of treatment, he was treated with Vigabatrin, Carbamazepine and Valproate. While switching from Carbamazepine to Valproate, he presented anemia but with no jaundice. His hemoglobin was 4.1g/dl bone-marrow biopsy revealed erythroid hypoplasia...

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