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Original Article

Distribution and Expression of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid(AMPA) Receptor Subunits in Moderate Hypoxic Newborn Piglet Brain

Na Yeon Kim, Woo Taek Ki

Clin Exp Pediatr. 1999;42(2):239-248. Published online February 15, 1999

Purpose : The mechanism of hypoxic damage is mainly intracellular influx of calcium ions through the glutamate ionotropic receptor(NMDA, AMPA/kainate). This study was performed to determine alterations in distribution and expression of AMPA receptor subunits after 1-hour of moderate hypoxia in the newborn piglet brain, in a state of mild to moderate perinatal hypoxic-ischemic encephalopathy. Methods : Ten newborn piglets were...

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