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Original Article

Relationship between Gb3 Expression and Cytotoxicity of Shiga-like Toxin I

Suk-Hwan Lim, Gi-Young Kim, Hyung-Chun Kim, Young-Hee Kim, Yong-Hae Son, Yang-Hyo Oh, Yeong-Min Park

Clin Exp Pediatr. 2003;46(2):143-153. Published online February 15, 2003

Purpose : Infection with Shiga-like toxin (SLT)-producing Escherichia coli, an emerging human pathogen found particularly in young children under 5 years of age, causes a spectrum of illnesses with high morbidity and mortality, ranging from diarrhea to hemorrhagic colitis and hemolytic uremic syndrome. Host mediators play an important role in the pathogenesis of SLT-I toxicity. The experiments described here were...

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