Clinical and Experimental Pediatrics

Search

Page Path

HOME
Search

Original Article

Thyroid peroxidase gene variants and susceptibility to congenital hypothyroidism and autoimmune thyroid disease among Egyptian pediatric cohort

Hala M. Sakhr, Mohammed H. Hassan, Esraa Abbass Abdallah, Amira Mahmoud Ewis, Mohamed Hesham Mohamed, Shymaa Gaber Rizk

Background: Pediatric thyroid disorders arise from complex interactions among genetic susceptibility, immune dysregulation, and metabolic factors that influence their onset and severity.
Purpose: This study aimed to evaluate the clinical, biochemical, micronutrient, and genetic determinants of thyroid dysfunction in children with particular emphasis on the thyroid peroxidase (TPO) Arg386His and Thr725Pro polymorphisms. Methods: This case-control study enrolled 150 Egyptian children aged 2–15...

DOI: https://doi.org/10.3345/cep.2025.02957 [Accepted]

MOST CITED ACCEPTED ARTICLES

Cited By 42	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis
Cited By 31	Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies
Cited By 30	Community-acquired pneumonia in children: updated perspectives on its etiology, diagnosis, and treatment
Cited By 25	Metabolic complications of obesity in children and adolescents
Cited By 22	Development of orphan drugs for rare diseases

+more

Thyroid peroxidase gene variants and susceptibility to congenital hypothyroidism and autoimmune thyroid disease among Egyptian pediatric cohort

Classification of neurocognitive impairment in pediatric drug-resistant focal epilepsy by quantifying seizure-affected brain network abnormalities in clinical diffusion-weighted imaging connectome

Effects of induction-phase acute kidney injury and age at diagnosis on chronic kidney disease in pediatric acute lymphoblastic leukemia: a time-to-event cohort study

Context-dependent features of transcriptomic landscapes in pregnant mother-neonate dyads of preeclampsia

Long-term outcome in children with infantile epileptic spasms syndrome: a multicenter retrospective study in Korea

+more

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES

FOR CONTRIBUTORS

ABOUT

Editorial Office: Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306 Fax: +82-2-3473-7307 E-mail: office@e-cep.org

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)