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Original Article
A Prospective Study on Ceftriaxone-associated Biliary Pseudolithiasis : A Dose-related Comparison
Sun Ju Lee, Jun Ho Kim, Jin Hwa Jeong, Sung Min Cho, Sung Tae Park, Dae Seob Choi, Hyeon Kyeong Lee
Clin Exp Pediatr. 2000;43(8):1090-1097.   Published online August 15, 2000
Purpose : Ceftriaxone, a parenteral third-generation cephalosporine, is widely used in the treatment of various bacterial infections. It possesses high calcium-binding affinity, forming complexes with calcium in bile salts to develop precipitate that mimics gallstone on ultrasonography. Biliary pseudolithiasis resolves completely with cessation of therapy, but several symptomatic patients have undergone cholesystectomy. We prospectively evaluated the incidence, risk factors and...